中药对鳗鲡病原菌的体外抑制作用

CORC > 集美大学

	中药对鳗鲡病原菌的体外抑制作用
	李忠琴 ; 关瑞章 ; 汪黎虹 ; 刘宏伟
刊名	http://epub.edu.cnki.net/grid2008/brief/detailj.aspx?filename=hnnd201103020&dbcode=CJFQ&dbname=CJFQ2011
	2012-06-05 ; 2012-06-05
关键词	鳗鲡病原菌中药抑菌活性 eel pathogenic bacteria Chinese herbs antibacterial activity S948
其他题名	Antibacterial activity of Chinese herbs against pathogenic bacteria from eels in vitro
中文摘要	研究虎杖、石榴皮、大黄、黄芩、五倍子、黄连、冬凌草、独活、贯众、木贼草等10种中药材单用和五倍子、大黄、石榴皮、虎杖、黄芩、黄连两两联用(15种配方)对从养殖病鳗中分离得到的12株常见病原菌的抑菌作用。结果表明:中药单用对病原菌均有不同程度的抑制作用,其中,五倍子的抑菌作用最强,其次是大黄和石榴皮,木贼草的抑菌作用最差;中药联用呈现协同效应(FIC<1)的占68.3%,其中有显著协同效应(FIC≤0.5)的占26.0%,与中药单用相比,中药联用对大多数病原菌的抑制作用增强,且可大大减少单一中药的给药浓度。; To study antibacterial activity of Chinese herbs as Scutellaria baicalensis Georgi,Coptis chinensis Franch,Rhus chinensis Mill,and so on,and their double-compounds, minimum inhibitory concentration (MIC) of single Chinese herb and the compounds against twelve pathogenic bacteria from eels were measured by agar dilution method. The results showed that ten kinds of Chinese herbs had antibacterial effect in different extent on the twelve bacteria. Rhus chinensis Mill had the best antibacterial activity, followed by Rheum palmatum Linn and Punica granatum Linn, and Equisetumra mosissimum Desf had the smallest antibacterial activity. Fifteen combinations had synergism antibacterial effects against pathogenic bacteria. Compared to single Chinese herb, antibacterial activity of almost all compounds had increased. The fractional inhibitory concentration (FIC) index of <1, was detected in 68.3% of the compounds, and FIC index of ≤0.5 was detected in 26.0% of the compounds. The study also indicated that rational use of Chinese herbal compounds not only can increase drug antimicrobial efficacy, but also can significantly reduce the concentration of Chinese herbs in the compounds.; 【作者单位】集美大学水产学院；教育部鳗鱼产业技术工程研究中心；【作者英文名】LI Zhong-qin1,2, GUAN Rui-zhang1,2, WANG Li-hong1,2, LIU Hong-wei1,2 (1.College of Fisheries, Jimei University, Xiamen, Fujian 361021, China; 2.Ministry of Education, Engineering Research Center of Eel Modern Industrial Technology, Xiamen, Fujian 361
语种	中文
内容类型	期刊论文
源URL	[http://ir.calis.edu.cn/hdl/235041/12127]
专题	集美大学
推荐引用方式 GB/T 7714	李忠琴,关瑞章,汪黎虹,等. 中药对鳗鲡病原菌的体外抑制作用[J]. http://epub.edu.cnki.net/grid2008/brief/detailj.aspx?filename=hnnd201103020&dbcode=CJFQ&dbname=CJFQ2011,2012, 2012.
APA	李忠琴,关瑞章,汪黎虹,&刘宏伟.(2012).中药对鳗鲡病原菌的体外抑制作用.http://epub.edu.cnki.net/grid2008/brief/detailj.aspx?filename=hnnd201103020&dbcode=CJFQ&dbname=CJFQ2011.
MLA	李忠琴,et al."中药对鳗鲡病原菌的体外抑制作用".http://epub.edu.cnki.net/grid2008/brief/detailj.aspx?filename=hnnd201103020&dbcode=CJFQ&dbname=CJFQ2011 (2012).