| Two-Photon Fluorescent Probes of Biological Zn(II) Derived from 7-Hydroxyquinoline | |
| Chen, Xiao-Yun ; Shi, Jing ; Li, Yi-Ming ; Wang, Feng-Liang ; Wu, Xu ; Guo, Qing-Xiang ; Liu, Lei | |
| 2010-10-12 ; 2010-10-12 | |
| 关键词 | ZINC IONS LIVING TISSUE NEURONAL ZINC SENSOR ZN2+ FLUOROPHORE MICROSCOPY DESIGN CHEMOSENSORS DERIVATIVES Chemistry, Organic |
| 中文摘要 | A new fluorescent probe for monitoring Zn2+ was synthesized based on the structure of 7-hydroxyquinoline. Compared with 8-substituted quinolines, the new probe exhibited higher selectivity for Zn2+ over Cd2+. Its fluorescence enhancement (14-fold) and nanomolar range sensitivity (K-d = 0.117 nM) were favorable toward biological applications. Experiments also showed that a cell-permeable derivative of the new probe was potentially useful for two-photon imaging in living |
| 语种 | 英语 ; 英语 |
| 出版者 | AMER CHEMICAL SOC ; WASHINGTON ; 1155 16TH ST, NW, WASHINGTON, DC 20036 USA |
| 内容类型 | 期刊论文 |
| 源URL | [http://hdl.handle.net/123456789/81070]  |
| 专题 | 清华大学 |
| 推荐引用方式 GB/T 7714 | Chen, Xiao-Yun,Shi, Jing,Li, Yi-Ming,et al. Two-Photon Fluorescent Probes of Biological Zn(II) Derived from 7-Hydroxyquinoline[J],2010, 2010. |
| APA | Chen, Xiao-Yun.,Shi, Jing.,Li, Yi-Ming.,Wang, Feng-Liang.,Wu, Xu.,...&Liu, Lei.(2010).Two-Photon Fluorescent Probes of Biological Zn(II) Derived from 7-Hydroxyquinoline.. |
| MLA | Chen, Xiao-Yun,et al."Two-Photon Fluorescent Probes of Biological Zn(II) Derived from 7-Hydroxyquinoline".(2010). |
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