| Electrospray ionization tandem mass spectrometric characteristics of d4T H-phosphonate and distamycin conjugates | |
| Ding, Jingjing ; Qian, Ning ; Li, Chao ; Qiao, Renzhong ; Zhao, Yufen | |
| 2010-10-12 ; 2010-10-12 | |
| 关键词 | DNA MINOR-GROOVE ESI-MS CHARACTERISTICS POLYAMINE AMIDES RECOGNITION BINDING SPECTRA ANALOGS AZT DERIVATIVES ALKYLATION Chemistry, Analytical Spectroscopy |
| 中文摘要 | The study of the dissociation of the protonated molecular species [M+H](+) and selected fragment ions allowed proposals for the main fragmentation pathways of the title compounds. The main fragments are formed by expelling a molecule of thymine, thymidine (d4T) or isopropyl. The most striking feature of the tandem mass (MS/MS) spectra is the cleavage of C-CO bonds between N-methylpyrrole and carbonyl groups in the presence of the amidine. Electrospray ionization is proven to be a good method for the structural characterization and identification of these kinds of compounds. Copyright (C) 2009 John Wiley & Sons, Ltd. |
| 语种 | 英语 ; 英语 |
| 出版者 | JOHN WILEY & SONS LTD ; CHICHESTER ; THE ATRIUM, SOUTHERN GATE, CHICHESTER PO19 8SQ, W SUSSEX, ENGLAND |
| 内容类型 | 期刊论文 |
| 源URL | [http://hdl.handle.net/123456789/80990]  |
| 专题 | 清华大学 |
| 推荐引用方式 GB/T 7714 | Ding, Jingjing,Qian, Ning,Li, Chao,et al. Electrospray ionization tandem mass spectrometric characteristics of d4T H-phosphonate and distamycin conjugates[J],2010, 2010. |
| APA | Ding, Jingjing,Qian, Ning,Li, Chao,Qiao, Renzhong,&Zhao, Yufen.(2010).Electrospray ionization tandem mass spectrometric characteristics of d4T H-phosphonate and distamycin conjugates.. |
| MLA | Ding, Jingjing,et al."Electrospray ionization tandem mass spectrometric characteristics of d4T H-phosphonate and distamycin conjugates".(2010). |
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