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	Structure Modification of Resveratrol and Pharmacological Activity
	Liu Huachen ; Dong Aijun ; Gao Chunmei ; Jiang Yuyang
	2010-10-12 ; 2010-10-12
关键词	resveratrol pharmacological activity structure-activity relationships CONFORMATIONALLY RESTRICTED ANALOGS BIOLOGICAL EVALUATION CYTOTOXIC EVALUATION TRANS-RESVERATROL INHIBITORY-ACTIVITY ANTITUMOR-ACTIVITY ANTICANCER AGENTS NITRIC-OXIDE CELL-CYCLE IN-VIVO Chemistry, Multidisciplinary
中文摘要	In order to improve activity and decrease toxicity, searching for lead compounds with biological activity existed in the nature and modifying their structures is an important means of innovation of new drugs. Resveratrol, a phytoalexin isolated from grapes and other plants, is well-known for its potent chemopreventive properties towards the most severe contemporary human diseases, such as cancer, vascular disease, neurodegenerative disease and viral infection, etc. In recent years, more and more scientists modify the double bond or benzene ring of resveratrol to get higher activity, lower toxicity derivates. In this paper, the structure-activity relationships and pharmacological properties of the resveratrol derivatives as a potent chemopreventive agent are reviewed and discussed.
语种	中文 ; 中文
出版者	CHINESE ACAD SCIENCES ; BEIJING ; NO. 33 BEISIHUANXILU, ZHONGGUANCUN, BEIJING 100080, PEOPLES R CHINA
内容类型	期刊论文
源URL	[http://hdl.handle.net/123456789/80835]
专题	清华大学
推荐引用方式 GB/T 7714	Liu Huachen,Dong Aijun,Gao Chunmei,et al. Structure Modification of Resveratrol and Pharmacological Activity[J],2010, 2010.
APA	Liu Huachen,Dong Aijun,Gao Chunmei,&Jiang Yuyang.(2010).Structure Modification of Resveratrol and Pharmacological Activity..
MLA	Liu Huachen,et al."Structure Modification of Resveratrol and Pharmacological Activity".(2010).

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