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Label-free electronic detection of DNA using simple double-walled carbon nanotube resistors
Xiaochen Dong ; Dongliang Fu ; Yanping Xu ; Jinquan Wei ; Yumeng Shi ; Peng Chen ; Lain-Jong Li
2010-10-12 ; 2010-10-12
关键词Practical Experimental/ biosensors carbon nanotubes DNA electrochemical sensors molecular biophysics nanosensors photoresists resistors/ label-free electronic detection DNA hybridization double-walled carbon nanotube resistor drop-casted doubled-walled carbon nanotube networks DNA concentration photoresists location-selective capping charge-transfer model C/ A8780B Biosensors A8715B Biomolecular structure, configuration, conformation, and active sites A8280F Electrochemical analytical methods A8280T Chemical sensors B7230J Biosensors B7230M Microsensors and nanosensors B7230L Chemical sensors B7320T Chemical variables measurement/ C/el
中文摘要Label-free electrical detection of DNA hybridization using resistive sensing devices based on drop-casted doubled-walled carbon nanotube (DWNT) networks and as-grown films is presented. Sensitive, selective, and reliable detection of DNA hybridization is achieved by simple two-terminal measurements, which is suitable for the hand-held type of device applications. Our approach is able to detect DNA concentrations ranging from 50 to 500 nM. Utilizing location-selective capping by photoresists, we designed experiments to reveal the sensing mechanism and found that the carbon nanotube (CNT)-metal junction may not play a dominant role in sensing as it does in single-walled carbon nanotube-based transistor devices. A charge- transfer model is proposed to explain the detection mechanism.
语种英语
出版者American Chemical Society ; USA
内容类型期刊论文
源URL[http://hdl.handle.net/123456789/80600]  
专题清华大学
推荐引用方式
GB/T 7714
Xiaochen Dong,Dongliang Fu,Yanping Xu,et al. Label-free electronic detection of DNA using simple double-walled carbon nanotube resistors[J],2010, 2010.
APA Xiaochen Dong.,Dongliang Fu.,Yanping Xu.,Jinquan Wei.,Yumeng Shi.,...&Lain-Jong Li.(2010).Label-free electronic detection of DNA using simple double-walled carbon nanotube resistors..
MLA Xiaochen Dong,et al."Label-free electronic detection of DNA using simple double-walled carbon nanotube resistors".(2010).
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