Label-free electronic detection of DNA using simple double-walled carbon nanotube resistors | |
Xiaochen Dong ; Dongliang Fu ; Yanping Xu ; Jinquan Wei ; Yumeng Shi ; Peng Chen ; Lain-Jong Li | |
2010-10-12 ; 2010-10-12 | |
关键词 | Practical Experimental/ biosensors carbon nanotubes DNA electrochemical sensors molecular biophysics nanosensors photoresists resistors/ label-free electronic detection DNA hybridization double-walled carbon nanotube resistor drop-casted doubled-walled carbon nanotube networks DNA concentration photoresists location-selective capping charge-transfer model C/ A8780B Biosensors A8715B Biomolecular structure, configuration, conformation, and active sites A8280F Electrochemical analytical methods A8280T Chemical sensors B7230J Biosensors B7230M Microsensors and nanosensors B7230L Chemical sensors B7320T Chemical variables measurement/ C/el |
中文摘要 | Label-free electrical detection of DNA hybridization using resistive sensing devices based on drop-casted doubled-walled carbon nanotube (DWNT) networks and as-grown films is presented. Sensitive, selective, and reliable detection of DNA hybridization is achieved by simple two-terminal measurements, which is suitable for the hand-held type of device applications. Our approach is able to detect DNA concentrations ranging from 50 to 500 nM. Utilizing location-selective capping by photoresists, we designed experiments to reveal the sensing mechanism and found that the carbon nanotube (CNT)-metal junction may not play a dominant role in sensing as it does in single-walled carbon nanotube-based transistor devices. A charge- transfer model is proposed to explain the detection mechanism. |
语种 | 英语 |
出版者 | American Chemical Society ; USA |
内容类型 | 期刊论文 |
源URL | [http://hdl.handle.net/123456789/80600] ![]() |
专题 | 清华大学 |
推荐引用方式 GB/T 7714 | Xiaochen Dong,Dongliang Fu,Yanping Xu,et al. Label-free electronic detection of DNA using simple double-walled carbon nanotube resistors[J],2010, 2010. |
APA | Xiaochen Dong.,Dongliang Fu.,Yanping Xu.,Jinquan Wei.,Yumeng Shi.,...&Lain-Jong Li.(2010).Label-free electronic detection of DNA using simple double-walled carbon nanotube resistors.. |
MLA | Xiaochen Dong,et al."Label-free electronic detection of DNA using simple double-walled carbon nanotube resistors".(2010). |
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