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	Hyperthermia by a nitinol stent in an alternating magnetic field: Safety and feasibility in rabbit esophageal cancer
	Zhou, Jumei ; Li, Ning ; Xia, Qisheng ; Du, Lehui ; Wang, Xiaowen ; Zhao, Linyun ; Wang, Xufei ; Tang, Jintian
	2010-10-12 ; 2010-10-12
关键词	Hyperthermia Nitinol stent Alternating magnetic field Rabbit Esophageal tumor SQUAMOUS-CELL CARCINOMA TUMOR RESPONSE METAL STENTS THERAPY EXPRESSION P53 Multidisciplinary Sciences
中文摘要	Hyperthermia by heating in-stent is a potentially new method to treat esophageal cancer. This study assessed the safety of heating the rabbit esophagus with a nitinol stent in an alternating magnetic field (AMF) and investigated whether this method offers a therapeutic option for esophageal cancer. Nitinol stents were placed in the cervical esophagi of healthy rabbits, which were heated in an AMF for different times at 43, 46 and 50 degrees C. The esophagi were histologically examined after a week to observe whether there was transmural necroses. Then esophageal cancer of rabbit placed nitinol stents were heated in an AMF at 46 degrees C for 10 min. Stents were heated to a target temperature within 5 min. The highest tolerated temperature and time for the healthy rabbit esophagus was at 46 degrees C for 10 min. Tumor growth was delayed by heating and it was statistically significant. Heating the rabbit esophageal wall at 46 degrees C for 10 min proves to be safe and effective in delaying tumor growth. (C) 2009 National Natural Science Foundation of China and Chinese Academy of Sciences. Published by Elsevier Limited and Science in China Press. All rights reserved.
语种	英语 ; 英语
出版者	ELSEVIER SCIENCE INC ; NEW YORK ; 360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA
内容类型	期刊论文
源URL	[http://hdl.handle.net/123456789/78850]
专题	清华大学
推荐引用方式 GB/T 7714	Zhou, Jumei,Li, Ning,Xia, Qisheng,et al. Hyperthermia by a nitinol stent in an alternating magnetic field: Safety and feasibility in rabbit esophageal cancer[J],2010, 2010.
APA	Zhou, Jumei.,Li, Ning.,Xia, Qisheng.,Du, Lehui.,Wang, Xiaowen.,...&Tang, Jintian.(2010).Hyperthermia by a nitinol stent in an alternating magnetic field: Safety and feasibility in rabbit esophageal cancer..
MLA	Zhou, Jumei,et al."Hyperthermia by a nitinol stent in an alternating magnetic field: Safety and feasibility in rabbit esophageal cancer".(2010).

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