| 毛细管电泳分析7-氨基头孢霉烷酸生产过程 | |
| 童忆舟 ; 李强 ; 罗晖 ; TONG Yi-Zhou ; LI Qiang ; LUO Hui | |
| 2010-06-10 ; 2010-06-10 | |
| 关键词 | 7-氨基头孢霉烷酸 头孢菌素C 戊二酰基-7-氨基头孢霉烷酸 高效毛细管电泳 测定 7-aminocephalosporanic acid cephalosporin C glutaryl-7-aminocephalosporanic acid HPCE determination TQ465.1 |
| 其他题名 | HPCE Determination in Production of 7-Aminocephalosporanic Acid |
| 中文摘要 | 建立了高效毛细管电泳分析法检测7-氨基头孢霉烷酸生产过程。采用未涂层石英毛细管柱,缓冲液为0.01mol/L磷酸盐缓冲液(pH 8.0),运行电压30kV,检测波长254nm。7-氨基头孢霉烷酸、头孢菌素C和戊二酰基-7-氨基头孢霉烷酸的线性范围(mg/ml)分别为0.05～3(r=0.998)、0.1～3.5(r=0.992)和0.1～5(r=0.996),迁移时间和峰面积的RSD分别为0.5%、1.0%、0.6%和2.2%、3.0%、2.4%。; A high performance capillary electrophoresis was established for the determination in the production of7-aminocephalosporanic acid. An uncoated fused silica capillary column was used with the running buffer solution of0.01mol/L phosphate buffer (pH 8.0), at the detection wavelength of 254nm. The running voltage was 30kV. The linearranges of 7-aminocephalosporanic acid, cephalosporin C and glutaryl-7-aminocephalosporanic acid were 0.05 - 3mg/ml (r=0.998), 0.1 - 3.5mg/ml (r=0.992) and 0.1 - 5mg/ml (r=0.996), respectively. The RSDs of migration times and areaswere 0.5%, 1.0%, 0.6% and 2.2 %, 3.0%, 2.4%, respectively. |
| 语种 | 中文 ; 中文 |
| 内容类型 | 期刊论文 |
| 源URL | [http://hdl.handle.net/123456789/63964]  |
| 专题 | 清华大学 |
| 推荐引用方式 GB/T 7714 | 童忆舟,李强,罗晖,等. 毛细管电泳分析7-氨基头孢霉烷酸生产过程[J],2010, 2010. |
| APA | 童忆舟,李强,罗晖,TONG Yi-Zhou,LI Qiang,&LUO Hui.(2010).毛细管电泳分析7-氨基头孢霉烷酸生产过程.. |
| MLA | 童忆舟,et al."毛细管电泳分析7-氨基头孢霉烷酸生产过程".(2010). |
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