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	黄连-吴茱萸药对不同配伍方式的红外光谱研究
	武彦文 ; 孙素琴 ; 肖小河 ; 张经华 ; 金城 ; WU Yan-wen ; SUN Su-qin ; XIAO Xiao-he ; ZHANG Jing-hua ; JIN Cheng
	2010-06-10 ; 2010-06-10
关键词	中药复方 配伍 红外光谱 黄连-吴茱萸 Chinese herb preparation Compatibility FTIR Coptidis-evodia R284 R289
其他题名	Study on Compatibility of Coptidis-Evodia Couples by FTIR Spectroscopy
中文摘要	中药复方配伍规律是中医药研究的重点,该文将红外光谱技术特有的宏观指纹特性与中医辨证施治的整体理论相结合,旨在建立一种既能反映中医药整体观的整合调节作用,又具有普遍适用于中药复方和快速、经济特点的研究模式。左金丸与其类方反左金、甘露散和茱萸丸是寒热配伍的经典方剂,它们都是由黄连和吴茱萸以不同比例组成的对药。文章通过分析比较单味药黄连、吴茱萸及其以不同配伍方式组成的黄连-吴茱萸类方的红外光谱图,对这4个药对复方的红外谱图进行特征峰指认,结果发现单味药黄连不仅在左金丸和甘露散中占绝对优势,而且在茱萸丸的水提物中贡献率也比吴茱萸大;此外,在茱萸丸和反左金的醇提物中,黄连亦表现出高于吴茱萸的整体贡献率。; Combining unique macro-fingerprint characteristics of infrared spectroscopy(IR) with the overall concept of traditional Chinese medicine(TCM) theory,the authors seek to establish a new,rapid and economic method for research on Chinese herb preparation(CHP),which could reflect the whole and integration concept of TCM theory and also be widely applied in TCM research.In the present paper,four coptidis-evodia couples,e.g.Zuo-jin-wan(coptidis∶evodia=6∶1),Gan-lu-san(coptidis∶evodia=2∶1),Zhu-yu-wan(coptidis∶evodia=1∶1) and Fan-zuo-jin(coptidis∶evodia=1∶6),were extracted by boiling water and 80% alcohol,and the FTIR spectra of those CHPs were compared and analyzed in detail.The characteristic absorbance bands of coptidis and evodia were assigned in the FTIR spectra of the four coptidis-evodia couples.The results showed that rhizoma coptidis owns absolute superiority in both extracts of Zuo-jin-wan and Gan-lu-san since the proportions of rhizoma coptidis in the two couples are higher than those of fructus evodiae.With regard to Zhu-yu-wan,the proportions of two ingredients are the same.However,the contribution rate of coptidis is higher than that of evodiae in water extract of Zhu-yu-wan.In addition,coptidis also shows higher contribution rate than that of evodia in alcohol extract of Fan-zuo-jin.The spectroscopic technique described here is a simple and rapid analytical technique,which could provide valuable chemical information about the whole coptidis-evodia CHPs.; 中国博士后基金项目(20060400073); 国家自然科学基金项目(30701107); 国家“973”课题项目(2006CB504703)资助
语种	中文 ; 中文
内容类型	期刊论文
源URL	[http://hdl.handle.net/123456789/61038]
专题	清华大学
推荐引用方式 GB/T 7714	武彦文,孙素琴,肖小河,等. 黄连-吴茱萸药对不同配伍方式的红外光谱研究[J],2010, 2010.
APA	武彦文.,孙素琴.,肖小河.,张经华.,金城.,...&JIN Cheng.(2010).黄连-吴茱萸药对不同配伍方式的红外光谱研究..
MLA	武彦文,et al."黄连-吴茱萸药对不同配伍方式的红外光谱研究".(2010).

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