| 大鼠去势后肾上腺与前列腺中Cyp17a1基因的表达 | |
| 王琬 ; 何永鑫 ; 陈君 ; 李雪 ; 罗国安 ; 王义明 ; WANG Wan ; HE Yong-Xin ; CHEN Jun ; LI Xue ; LUO Guo-An ; WANG Yi-Ming | |
| 2010-05-13 ; 2010-05-13 | |
| 关键词 | Cyp17a1 肾上腺 前列腺 实时荧光定量PCR Cyp17a1 Adrenal Prostate Real-time fluorescent quantitative PCR R737.25 |
| 其他题名 | Cyp17a1 Gene Expression in Rat′s Adrenal and Prostate After Orchiectomy |
| 中文摘要 | 通过定量检测大鼠去势前后肾上腺和前列腺中Cyp17a1基因的表达,试图从分子水平解释去势手术后大鼠机体内雄性激素水平的变化.; In this paper the change law of Cyp17a1 gene expression in the process was studied, in which the rats′ adrenal secretes androgen after orchiectomy. The Cyp17a1 gene expression in adrenal and prostate tissues was detected via real-time fluorescent quantitative PCR on different time points, which were before orchiectomy and 1 week, 2 weeks, 3 weeks, 4 weeks after orchiectomy, respectively. The results indicate that Cyp17a1 gene expression in adrenal would increase after orchiectomy, and reach the maximum when 3 weeks after. That Cyp17a1 gene exists in rat′s prostate tissue was discovered for the first time. The conclusion is that adrenal have the function of compensation, increasing the secretion of androgen after orchiectomy. It is presumed that prostatecan synthesizes DHEA as well. |
| 语种 | 中文 ; 中文 |
| 内容类型 | 期刊论文 |
| 源URL | [http://hdl.handle.net/123456789/31741]  |
| 专题 | 清华大学 |
| 推荐引用方式 GB/T 7714 | 王琬,何永鑫,陈君,等. 大鼠去势后肾上腺与前列腺中Cyp17a1基因的表达[J],2010, 2010. |
| APA | 王琬.,何永鑫.,陈君.,李雪.,罗国安.,...&WANG Yi-Ming.(2010).大鼠去势后肾上腺与前列腺中Cyp17a1基因的表达.. |
| MLA | 王琬,et al."大鼠去势后肾上腺与前列腺中Cyp17a1基因的表达".(2010). |
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