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	Monitoring cerebral oxygen saturation during cardiopulmonary bypass using near-infrared spectroscopy: the relationships with body temperature and perfusion rate
	Teng, YC ; Ding, HS ; Gong, QC ; Jia, ZS ; Huang, L
	2010-05-11 ; 2010-05-11
关键词	near infrared spectroscopy regional cerebral oxygen saturation cardiopulmonary bypass calibration body temperature perfusion rate OPTICAL-PROPERTIES LIGHT-PROPAGATION TISSUE OXIMETER ADULT MODEL HEAD Biochemical Research Methods Optics Radiology, Nuclear Medicine & Medical Imaging
中文摘要	During cardiopulmonary bypass (CPB) because of weak arterial pulsation, near-IR spectroscopy (NIRS) is almost the only available method to monitor cerebral oxygenation noninvasively. Our group develops a NIRS oximeter to monitor regional cerebral oxygenation especially its oxygen saturation (rScO(2)). To achieve optimal coupling between the sensor and human brain, the distances between the light source and the detectors on it are properly chosen. The oximeter is calibrated by blood gas analysis, and the results indicate that its algorithm is little influenced by either background absorption or overlying tissue. We used it to measure the rScO(2) of 15 patients during CPB. It is shown that rScO(2) is negatively correlated with body temperature and positively with perfusion rate. There are two critical stages during CPB when rScO(2) might be relatively low: one is the low-perfusion-rate stage, the other is the early rewarming stage. During cooling, the changes of total hemoglobin concentration (C-tHb) compared with its original value is also monitored. It is shown that CtHb decreases to a small extent, which may mainly reflect cerebral vasoconstriction induced by cooling. All these results indicate that NIRS can be used to monitor cerebral oxygenation to protect cerebral tissue during CPB. (c) 2006 Society of Photo-Optical Instrumentation Engineers.
语种	英语 ; 英语
出版者	SPIE-INT SOCIETY OPTICAL ENGINEERING ; BELLINGHAM ; 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98225 USA
内容类型	期刊论文
源URL	[http://hdl.handle.net/123456789/27630]
专题	清华大学
推荐引用方式 GB/T 7714	Teng, YC,Ding, HS,Gong, QC,et al. Monitoring cerebral oxygen saturation during cardiopulmonary bypass using near-infrared spectroscopy: the relationships with body temperature and perfusion rate[J],2010, 2010.
APA	Teng, YC,Ding, HS,Gong, QC,Jia, ZS,&Huang, L.(2010).Monitoring cerebral oxygen saturation during cardiopulmonary bypass using near-infrared spectroscopy: the relationships with body temperature and perfusion rate..
MLA	Teng, YC,et al."Monitoring cerebral oxygen saturation during cardiopulmonary bypass using near-infrared spectroscopy: the relationships with body temperature and perfusion rate".(2010).

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