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	Integrated genome-wide gene expression map and high-resolution analysis of aberrant chromosomal regions in squamous cell lung cancer
	Zhang, XY ; Hu, Y ; Cui, YP ; Miao, XP ; Tian, F ; Xia, YJ ; Wu, YQ ; Liu, XJ
	2010-05-11 ; 2010-05-11
关键词	microarray aberrant chromosomal region squamous cell carcinoma gene expression map moving-median method HYBRIDIZATION ANALYSIS ALLELIC IMBALANCE DISTINCT PATTERNS HIGH-LEVEL ADENOCARCINOMA CARCINOMAS HETEROZYGOSITY IDENTIFICATION MICROARRAYS FREQUENT Biochemistry & Molecular Biology Biophysics Cell Biology
中文摘要	The recognition of recurrent aberrant regions in cancer is important to the discovery of candidate cancer related genes. Here we first constructed a genome-wide gene expression map of squamous lung carcinoma from the Stanford Microarray Database. High-resolution detection of aberrant chromosomal regions was performed by using moving-median method. 84% (27 of 32) of our results were consistent with the previous studies of comparative genomic hybridization or loss of heterozygosity. One overrepresented region in Xq28 was newly discovered to be related to squamous cell lung carcinoma. These observations could be of great interest for further studies. (c) 2006 Published by Elsevier B.V. on behalf of the Federation of European Biochemical Societies.
语种	英语 ; 英语
出版者	ELSEVIER SCIENCE BV ; AMSTERDAM ; PO BOX 211, 1000 AE AMSTERDAM, NETHERLANDS
内容类型	期刊论文
源URL	[http://hdl.handle.net/123456789/27030]
专题	清华大学
推荐引用方式 GB/T 7714	Zhang, XY,Hu, Y,Cui, YP,et al. Integrated genome-wide gene expression map and high-resolution analysis of aberrant chromosomal regions in squamous cell lung cancer[J],2010, 2010.
APA	Zhang, XY.,Hu, Y.,Cui, YP.,Miao, XP.,Tian, F.,...&Liu, XJ.(2010).Integrated genome-wide gene expression map and high-resolution analysis of aberrant chromosomal regions in squamous cell lung cancer..
MLA	Zhang, XY,et al."Integrated genome-wide gene expression map and high-resolution analysis of aberrant chromosomal regions in squamous cell lung cancer".(2010).

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