| Sinulaflexiolides A-K, cembrane-type diterpenoids from the Chinese soft coral Sinularia flexibilis | |
| Wen, Ting ; Ding, Yi ; Deng, Zhiwei ; van Ofwegen, Leen ; Proksch, Peter ; Lin, Wenhan | |
| 2010-05-11 ; 2010-05-11 | |
| 关键词 | MARINE-INVERTEBRATES CYTOTOXIC CEMBRANOIDS INDIAN-OCEAN COELENTERATA OCTOCORALLIA ALCYONACEA COLLECTION LACTONES Plant Sciences Chemistry, Applied Chemistry, Medicinal Pharmacology & Pharmacy |
| 中文摘要 | A bioassay-guided fractionation and chemical examination of the soft coral Sinularia flexibilis resulted in the isolation and characterization of sinulaflexiolides A-K (1-11), along with sinulariolone (12), 5-dehydrosinularolide (13), capillolide (14), sinulariolide (15), 5,8-epoxy-9-acetoxysinulariolide (16), flexibilide (17), dihydroflexibilide (18), and the enantiomer of 14-deoxycrassin (19). Their structures were determined on the basis of extensive spectroscopic (IR, MS, 2D NMR) data analysis and by comparison with spectroscopic data reported in the literature. Sinulaflexiolides D and E showed selective inhibitory activity against the gastric gland carcinoma cell line BGC-823 at 8.5 and 0.12 mu M, respectively. |
| 语种 | 英语 ; 英语 |
| 出版者 | AMER CHEMICAL SOC ; WASHINGTON ; 1155 16TH ST, NW, WASHINGTON, DC 20036 USA |
| 内容类型 | 期刊论文 |
| 源URL | [http://hdl.handle.net/123456789/26762]  |
| 专题 | 清华大学 |
| 推荐引用方式 GB/T 7714 | Wen, Ting,Ding, Yi,Deng, Zhiwei,et al. Sinulaflexiolides A-K, cembrane-type diterpenoids from the Chinese soft coral Sinularia flexibilis[J],2010, 2010. |
| APA | Wen, Ting,Ding, Yi,Deng, Zhiwei,van Ofwegen, Leen,Proksch, Peter,&Lin, Wenhan.(2010).Sinulaflexiolides A-K, cembrane-type diterpenoids from the Chinese soft coral Sinularia flexibilis.. |
| MLA | Wen, Ting,et al."Sinulaflexiolides A-K, cembrane-type diterpenoids from the Chinese soft coral Sinularia flexibilis".(2010). |
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