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Determination of dopamine and its relativity of baicalin in rat nuclei after intravenous administration of flavonoids from Scutellariae radix
Chen, Long ; Zhang, Lujun ; Wang, Xueli ; Lin, Han ; Du, Lijun
2010-05-11 ; 2010-05-11
关键词baicalin dopamine cerebral nuclei neurotransmitter TRANSIENT CEREBRAL-ISCHEMIA OREN-GEDOKU-TO NEUROTRANSMITTERS BAICALENSIS DISORDERS INDUCTION MICE Biochemical Research Methods Biochemistry & Molecular Biology Chemistry, Analytical Pharmacology & Pharmacy
中文摘要Baicalin is an active component of Scutellariae radix extracts. It can cross the blood-brain barrier and distribute in cerebral nuclei. However, its mechanism and the effects on the nuclei where it accumulates remain unclear. We used an HPLC-electrochemical detection method to determine the dopamine in cerebral nuclei after intravenous administration of flavonoids from Scutellariae radix and analyzed the relativity between baicalin and DA in cerebral nuclei. We found that the dopamine system is another target system of brain function which baicalin acts on. Copyright (c) 2006 John Wiley & Sons, Ltd.
语种英语 ; 英语
出版者JOHN WILEY & SONS LTD ; CHICHESTER ; THE ATRIUM, SOUTHERN GATE, CHICHESTER PO19 8SQ, W SUSSEX, ENGLAND
内容类型期刊论文
源URL[http://hdl.handle.net/123456789/26682]  
专题清华大学
推荐引用方式
GB/T 7714
Chen, Long,Zhang, Lujun,Wang, Xueli,et al. Determination of dopamine and its relativity of baicalin in rat nuclei after intravenous administration of flavonoids from Scutellariae radix[J],2010, 2010.
APA Chen, Long,Zhang, Lujun,Wang, Xueli,Lin, Han,&Du, Lijun.(2010).Determination of dopamine and its relativity of baicalin in rat nuclei after intravenous administration of flavonoids from Scutellariae radix..
MLA Chen, Long,et al."Determination of dopamine and its relativity of baicalin in rat nuclei after intravenous administration of flavonoids from Scutellariae radix".(2010).
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