Phylogenetic and biochemical studies reveal a potential evolutionary origin of small heat shock proteins of animals from bacterial class A | |
Fu, XM ; Jiao, WW ; Chang, ZY | |
2010-05-11 ; 2010-05-11 | |
关键词 | chaperone small heat shock protein oligomer polydisperse monodisperse ALPHA-CRYSTALLIN CHAPERONE ACTIVITY SUBUNIT EXCHANGE QUATERNARY STRUCTURE METHANOCOCCUS-JANNASCHII MOLECULAR CHAPERONES OLIGOMER FORMATION IN-VITRO PLANTS COMPLEXES Biochemistry & Molecular Biology Evolutionary Biology Genetics & Heredity |
中文摘要 | Small heat shock proteins ( sHSPs), as one subclass of molecular chaperones, are important for cells to protect proteins under stress conditions. Unlike the large HSPs ( represented by Hsp60 and Hsp70), sHSPs are highly divergent in both primary sequences and oligomeric status, with their evolutionary relationships being unresolved. Here the phylogenetic analysis of a representative 51 sHSPs ( covering the six subfamilies: bacterial class A, bacterial class B, archae, fungi, plant, and animal) reveals a close relationship between bacterial class A and animal sHSPs which form an outgroup. Accumulating data indicate that the oligomers from bacterial class A and animal sHSPs appear to exhibit polydispersity, while those from the rest exhibit monodispersity. Together, the close evolutionary relationship and the similarity in oligomeric polydispersity between bacterial class A and animal sHSPs not only suggest a potential evolutionary origin of the latter from the former, but also imply that their oligomeric polydispersity is somehow a property determined by their primary sequences. |
语种 | 英语 ; 英语 |
出版者 | SPRINGER ; NEW YORK ; 233 SPRING STREET, NEW YORK, NY 10013 USA |
内容类型 | 期刊论文 |
源URL | [http://hdl.handle.net/123456789/26619] ![]() |
专题 | 清华大学 |
推荐引用方式 GB/T 7714 | Fu, XM,Jiao, WW,Chang, ZY. Phylogenetic and biochemical studies reveal a potential evolutionary origin of small heat shock proteins of animals from bacterial class A[J],2010, 2010. |
APA | Fu, XM,Jiao, WW,&Chang, ZY.(2010).Phylogenetic and biochemical studies reveal a potential evolutionary origin of small heat shock proteins of animals from bacterial class A.. |
MLA | Fu, XM,et al."Phylogenetic and biochemical studies reveal a potential evolutionary origin of small heat shock proteins of animals from bacterial class A".(2010). |
个性服务 |
查看访问统计 |
相关权益政策 |
暂无数据 |
收藏/分享 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论