| Candidate multi-peptide-vaccine against classical swine fever virus induced potent immunity with serological marker | |
| Dong, XN ; Chen, Y ; Wu, Y ; Chen, YH | |
| 2010-05-11 ; 2010-05-11 | |
| 关键词 | classical swine fever virus (CSFV) multi-peptide-vaccine (MPV) marker vaccines aluminum adjuvant HOG-CHOLERA VIRUS ALUMINUM EPITOPE Immunology Medicine, Research & Experimental Veterinary Sciences |
| 中文摘要 | Our previous study proposed a protective multi-peptide-vaccine (MPV) with Freund's adjuvant against classical swine fever virus (CSFV). In this study, another candidate MPV, using aluminum adjuvant, was further examined. All immunized pigs kept healthy during the experimental period, while the control group rapidly showed clinical symptoms and died. Moreover. anti-sera from MPV-immunized pigs could interact with peptides involved in the MPV. in contrast to anti-sera from non-immunized or infected ones, This property permits MPV-immunized pigs to be easily differentiated from infected ones with simple serological method. Therefore, this new MPV is suitable to act as a candidate marker vaccine against CSFV. © 2005 Elsevier Ltd. All rights reserved. |
| 语种 | 英语 ; 英语 |
| 出版者 | ELSEVIER SCI LTD ; OXFORD ; THE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND |
| 内容类型 | 期刊论文 |
| 源URL | [http://hdl.handle.net/123456789/26550]  |
| 专题 | 清华大学 |
| 推荐引用方式 GB/T 7714 | Dong, XN,Chen, Y,Wu, Y,et al. Candidate multi-peptide-vaccine against classical swine fever virus induced potent immunity with serological marker[J],2010, 2010. |
| APA | Dong, XN,Chen, Y,Wu, Y,&Chen, YH.(2010).Candidate multi-peptide-vaccine against classical swine fever virus induced potent immunity with serological marker.. |
| MLA | Dong, XN,et al."Candidate multi-peptide-vaccine against classical swine fever virus induced potent immunity with serological marker".(2010). |
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