Novel furostanol saponins from the bulbs of Allium macrostemon B. and their bioactivity on [Ca2+](i) increase induced by KCl | |
Chen, Hai-Feng ; Wang, Nai-Li ; Sun, Hong-Li ; Yang, Bao-Feng ; Yao, Xin-Sheng | |
2010-05-11 ; 2010-05-11 | |
关键词 | Allium macrostemon B novel furostanol saponins macrostemonoside M macrostemonoside N [Ca2+](i) increase TRITERPENOID SAPONINS VENTRICULAR MYOCYTES GLYCOSIDES Plant Sciences Chemistry, Applied Chemistry, Medicinal Pharmacology & Pharmacy |
中文摘要 | Chemical reinvestigation of the ethanol extract of the dried bulbs of Allium macrostemon B. led to the isolation of two novel furostanol saponins, named macrostemonoside M (1) and macrostemonoside N (2), together with six known saponins. The structures of new compounds were elucidated on the basis of extensive spectroscopic analysis including 1D and 2D NMR as (25 R )-22-hydroxy-5 beta-furostane-1 beta,2 beta,3 beta,6 alpha-tetraol-26- O -beta-d-glucopyranoside and 22-hydroxy-5 beta-furost-25-(27)-ene-1 beta,2 beta,3 beta,6 alpha-tetraol-26- O -beta-d-glucopyranoside, respectively. The pharmacological activities of all the saponins on [Ca2+](i) increase induced by KCl were evaluated. |
语种 | 英语 ; 英语 |
出版者 | TAYLOR & FRANCIS LTD ; ABINGDON ; 4 PARK SQUARE, MILTON PARK, ABINGDON OX14 4RN, OXON, ENGLAND |
内容类型 | 期刊论文 |
源URL | [http://hdl.handle.net/123456789/26344] |
专题 | 清华大学 |
推荐引用方式 GB/T 7714 | Chen, Hai-Feng,Wang, Nai-Li,Sun, Hong-Li,et al. Novel furostanol saponins from the bulbs of Allium macrostemon B. and their bioactivity on [Ca2+](i) increase induced by KCl[J],2010, 2010. |
APA | Chen, Hai-Feng,Wang, Nai-Li,Sun, Hong-Li,Yang, Bao-Feng,&Yao, Xin-Sheng.(2010).Novel furostanol saponins from the bulbs of Allium macrostemon B. and their bioactivity on [Ca2+](i) increase induced by KCl.. |
MLA | Chen, Hai-Feng,et al."Novel furostanol saponins from the bulbs of Allium macrostemon B. and their bioactivity on [Ca2+](i) increase induced by KCl".(2010). |
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