Low-temperature extrusion process of porous tubular scaffolds in tissue engineering | |
Zhang Lei ; Lin Feng ; Yan Yongnian ; Fei Xiaochen ; Sun Tao | |
2010-05-10 ; 2010-05-10 | |
关键词 | Practical/ elasticity extrusion gels phase separation porosity tissue engineering/ porous tubular scaffolds manufacture tissue engineering PEG/PBT gel thermally induced phase separation low-temperature extrusion process elasticity module human salivary gland cells/ A8770 Biomedical engineering A8780 Biophysical instrumentation and techniques E3628 Biotechnology industry E1520G Forming processes E2100 General mechanics |
中文摘要 | Solutions of PEG/PBT turn into gels below 20 degrees C. Porous tubular scaffolds were manufactured by extruding the gel with thermally induced phase separation in a low-temperature extrusion process. The influence of manufacturing temperature on the porosity, morphology and mechanical properties of the tubular scaffolds was analyzed in detail. The porosities of scaffolds, fabricated in the low temperature process are up to 95% with pore sizes of 35-48 mu m. The elasticity module of the scaffolds is between 61.9-106 kPa. Tests show that the scaffolds have favorable biocompatibility with human salivary gland (HSG) cells, which means that the scaffolds have promising applications in salivary gland tissue engineering. |
语种 | 中文 ; 中文 |
出版者 | Tsinghua Univ. Press ; China |
内容类型 | 期刊论文 |
源URL | [http://hdl.handle.net/123456789/23816] |
专题 | 清华大学 |
推荐引用方式 GB/T 7714 | Zhang Lei,Lin Feng,Yan Yongnian,et al. Low-temperature extrusion process of porous tubular scaffolds in tissue engineering[J],2010, 2010. |
APA | Zhang Lei,Lin Feng,Yan Yongnian,Fei Xiaochen,&Sun Tao.(2010).Low-temperature extrusion process of porous tubular scaffolds in tissue engineering.. |
MLA | Zhang Lei,et al."Low-temperature extrusion process of porous tubular scaffolds in tissue engineering".(2010). |
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