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	Extraction of hydrocortisone from the fermentation liquor with annular centrifugal contactors
	Zhou, JZ ; Duan, WH ; Zhou, XZ ; Zhang, CQ
	2010-05-10 ; 2010-05-10
关键词	annular centrifugal contactor hydrocortisone countercurrent extraction butyl acetate Chemistry, Multidisciplinary Engineering, Chemical
中文摘要	A continuous countercurrent extraction process for the recovery of hydrocortisone from the fermentation liquor has been developed with annular centrifugal contactors. When the hydrocortisone was extracted from the fermentation liquor with the butyl acetate, the distribution ratio increased with increase of the hydrocortisone concentration in the equilibrium aqueous phase. Both the laboratory tests and the plant tests have been finished with Phi 20 mm and Phi 230 mm annular centrifugal contactors respectively. In the laboratory tests, when the rotor speed was 3400 similar to 4200 r/min, the fermentation liquor flow was 30 similar to 50 mL/min and the phase ratio (V O /V A ) was 0.36 similar to 0.50, the percent recovery of hydrocortisone was higher than 92%. In the plant tests, when the rotor speed was 2000 r/min, the fermentation liquor flow was 2000 L/h and the butyl acetate flow was 1000 L/h, the percent recovery of hydrocortisone was about 96.5 similar to 98%.
语种	英语 ; 英语
出版者	TAYLOR & FRANCIS INC ; PHILADELPHIA ; 325 CHESTNUT ST, SUITE 800, PHILADELPHIA, PA 19106 USA
内容类型	期刊论文
源URL	[http://hdl.handle.net/123456789/23163]
专题	清华大学
推荐引用方式 GB/T 7714	Zhou, JZ,Duan, WH,Zhou, XZ,et al. Extraction of hydrocortisone from the fermentation liquor with annular centrifugal contactors[J],2010, 2010.
APA	Zhou, JZ,Duan, WH,Zhou, XZ,&Zhang, CQ.(2010).Extraction of hydrocortisone from the fermentation liquor with annular centrifugal contactors..
MLA	Zhou, JZ,et al."Extraction of hydrocortisone from the fermentation liquor with annular centrifugal contactors".(2010).

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