| Composition-graded films of fluoroapatite/PHB fabricated via electrospinning for tissue engineering | |
| Zhao, D. M. ; Wang, Y. X. ; Xu, R. W. ; Wu, G. ; Zhang, L. Q. ; Yu, D. S. ; Cui, F. Z. ; Chen, D. F. ; Tian, W. | |
| 2010-05-10 ; 2010-05-10 | |
| 关键词 | electrospinning fluoroapatite poly(3-hydroxybutyrate-co-4-hydroxybutyrate) tissue engineering gradient biocompatibility cytotoxicity POLYMER NANOFIBERS THERMAL-PROPERTIES HYDROXYAPATITE NANOCOMPOSITES FIBERS GENERATION MORPHOLOGY SCAFFOLDS HYDROGEL GELATIN Biotechnology & Applied Microbiology Materials Science, Biomaterials Polymer Science |
| 中文摘要 | Composition-graded films (CGF) of fluoroapatite (FAP) and poly(3-hydroxybutyrate-co-4-hydroxybutyrate) (PHB) were prepared via electrospinning solutions of FAP and PHB using a gradient composition of CGF. Thermal properties, mechanical properties and surface morphology of the films were investigated. Designed thermal and mechanical properties obtained by precise control of the composition gradient of the FAP/PHB CGF. The introduction of FAP in pure PHB film significantly changed the mechanical properties, such as tensile strength and extension rate of the pure PHB. Mouse fibroblast cells (L-929) were cultured on FAP/PHB uniform-films; the MTT test and cell morphology analysis indicate good biocompatibility of the modified CGF. This new method of processing makes CGF a potential candidate as an electrospinning scaffold material for tissue engineering. |
| 语种 | 英语 ; 英语 |
| 出版者 | SAGE PUBLICATIONS LTD ; LONDON ; 1 OLIVERS YARD, 55 CITY ROAD, LONDON EC1Y 1SP, ENGLAND |
| 内容类型 | 期刊论文 |
| 源URL | [http://hdl.handle.net/123456789/21742]  |
| 专题 | 清华大学 |
| 推荐引用方式 GB/T 7714 | Zhao, D. M.,Wang, Y. X.,Xu, R. W.,et al. Composition-graded films of fluoroapatite/PHB fabricated via electrospinning for tissue engineering[J],2010, 2010. |
| APA | Zhao, D. M..,Wang, Y. X..,Xu, R. W..,Wu, G..,Zhang, L. Q..,...&Tian, W..(2010).Composition-graded films of fluoroapatite/PHB fabricated via electrospinning for tissue engineering.. |
| MLA | Zhao, D. M.,et al."Composition-graded films of fluoroapatite/PHB fabricated via electrospinning for tissue engineering".(2010). |
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