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	In vitro degradation of porous nano-hydroxyapatite/collagen/PLLA scaffold reinforced by chitin fibres
	Qingling Feng ; Xiaoming Li ; Fuzhai Cui
	2010-05-10 ; 2010-05-10
关键词	Experimental/ biomechanics bone calcium compounds fibre reinforced composites Fourier transform spectra infrared spectra nanostructured materials polymers porous materials proteins scanning electron microscopy spectrochemical analysis tissue engineering/ in vitro degradation porous chitin fibre-reinforced scaffold bone tissue engineering nano-hydroxyapatite-collagen-poly-L-lactic acid composite dicyclobexylcarbodimide scanning electron microscopy chemical characteristics Fourier-transformed infrared spectroscopy interfacial bonding strength biomechanical property/ A8770M Biomedical materials A8745B Mechanical properties of tissues and organs A8280D Electromagnetic radiation spectrometry (chemical analysis)
中文摘要	In this paper, a novel porous scaffold for bone tissue engineering was prepared with nano-hydroxyapatite/collagen/Poly-l-lactic acid (PLLA) composite reinforced by chitin fibres. To enhance the strength of the scaffold further, PLLA was linked with chitin fibres by Dicyclohexylcarbodimide (DCC). The structures of the reinforced scaffold with and without linking were characterized by Scanning Electron Microscopy (SEM). The chemical characteristics of the chitin fibres with and without linking were evaluated by Fourier-transformed infrared (FTIR) spectroscopy. The mechanical performance during degradation in vitro was investigated. The results indicated that the nano-hydroxyapatite/collagen/PLLA composite reinforced by chitin fibres with linking kept better mechanical properties than that of the composite without linking. These results denoted that the stronger interfacial bonding strength of the scaffold with linking could decrease the degradation rate in vitro. The reinforced composite with the link-treatment can be severed as a scaffold for bone tissue engineering. [All rights reserved Elsevier].
语种	英语 ; 英语
出版者	Elsevier ; Netherlands
内容类型	期刊论文
源URL	[http://hdl.handle.net/123456789/21404]
专题	清华大学
推荐引用方式 GB/T 7714	Qingling Feng,Xiaoming Li,Fuzhai Cui. In vitro degradation of porous nano-hydroxyapatite/collagen/PLLA scaffold reinforced by chitin fibres[J],2010, 2010.
APA	Qingling Feng,Xiaoming Li,&Fuzhai Cui.(2010).In vitro degradation of porous nano-hydroxyapatite/collagen/PLLA scaffold reinforced by chitin fibres..
MLA	Qingling Feng,et al."In vitro degradation of porous nano-hydroxyapatite/collagen/PLLA scaffold reinforced by chitin fibres".(2010).

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