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Tissue engineering scaffold material and new bone growth
Tian Jiemo ; Dong Limin ; Wang Chen ; Guo Zhiping ; Zhang Chaozong ; Wang Xiaoyan ; Wang Xiangang ; Xu Wei ; Zan Qingfeng
2010-05-10 ; 2010-05-10
关键词Practical Experimental/ bioceramics bone calcium compounds patient treatment prosthetics tissue engineering/ tissue engineering scaffold material new bone growth beta -tricalcium phosphate hydroxyapatite surface bioactivity osteoblast attachment micro-CT test cultured bone marrow stromal cells implantation rabbits new bone formation bone reconstruction 3D porous structure pore size degradable biomaterials Ca/sub 3/PO/sub 4/ Ca/sub 10/(PO/sub 4/)/sub 6/(OH)/sub 2// A8770M Biomedical materials A8770J Prosthetics and other practical applications A8770G Patient care and treatment/ Ca3PO4/ss Ca3/ss PO4/ss Ca/ss O4/ss O/ss P/ss Ca10PO4OH/ss Ca10/ss PO4/ss Ca/ss O4/ss OH/ss H/ss O/ss P/ss
中文摘要This paper describes the structures of beta -TCP, beta -TCP/DCHA and HA, tests and analysis for their surface bioactivity and osteoblast attachment and the evaluation structure before or after implantation used by micro-CT test. The bone marrow stromal cells were cultured, or separation and proliferation were made to reach up to osteoblast concentration of 10/sup 5//cm/sup 3/, and then the osteoblasts were immersed in the biomaterials and implanted in the rabbits. The bone formation was observed and the mechanism of new bone formation was investigated. The experimental results after implantation show that introducing new bone grows into the scaffold holes, and scaffolds were degraded with new bone formation and growth. In the end, the bone was reconstructed. The results indicate these tissue-engineering scaffolds possess 3-D porous structure, pore size appropriate new bone growth, degradable, high bioactive and inducing new bone formation.
语种中文 ; 中文
出版者Northwest Inst. Nonferrous Met. Res ; China
内容类型期刊论文
源URL[http://hdl.handle.net/123456789/21152]  
专题清华大学
推荐引用方式
GB/T 7714
Tian Jiemo,Dong Limin,Wang Chen,et al. Tissue engineering scaffold material and new bone growth[J],2010, 2010.
APA Tian Jiemo.,Dong Limin.,Wang Chen.,Guo Zhiping.,Zhang Chaozong.,...&Zan Qingfeng.(2010).Tissue engineering scaffold material and new bone growth..
MLA Tian Jiemo,et al."Tissue engineering scaffold material and new bone growth".(2010).
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