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Penta-coordinate phosphorus intermediates analysis on phospho-related proteins
Wu, L ; Ma, Y ; Zhao, YF
2010-05-10 ; 2010-05-10
会议名称CHINESE JOURNAL OF CHEMISTRY ; 7th International Conference on Heteroatom Chemistry (ICHAC-7) ; Shanghai, PEOPLES R CHINA ; Web of Science
关键词penta-coordinate phosphorus intermediate square pyramid trigonal pyramid Chemistry, Multidisciplinary
中文摘要In this paper, based on known crystal structures of square pyramid (SP) and trigonal bipyramid (TBP) penta coordinated phosphorus compounds containing amino acid side chains, such as amino, carboxyl, hydroxyl or thiol, a software for survey the P(5)-structure of phosphorylated proteins was derived. By this software, it was found that 382 of 398 phosphorus related kinases (96%) from current PDB could go through the penta-coordinated phosphorus transition state or intermediate.
会议录出版者WILEY-V C H VERLAG GMBH ; WEINHEIM ; PO BOX 10 11 61, D-69451 WEINHEIM, GERMANY
语种英语 ; 英语
内容类型会议论文
源URL[http://hdl.handle.net/123456789/20003]  
专题清华大学
推荐引用方式
GB/T 7714
Wu, L,Ma, Y,Zhao, YF. Penta-coordinate phosphorus intermediates analysis on phospho-related proteins[C]. 见:CHINESE JOURNAL OF CHEMISTRY, 7th International Conference on Heteroatom Chemistry (ICHAC-7), Shanghai, PEOPLES R CHINA, Web of Science.
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