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Mathematical modeling of dynamic laser coagulation during laser-induced interstitial thermotherapy - art. no. 604709
Jiang, S. C. ; Zhang, X. X.
2010-05-10 ; 2010-05-10
会议名称Fourth International Conference on Photonics and Imaging in Biology and Medicine, Pts 1 and 2 ; 4th International Conference on Photonics and Imaging in Biology and Medicine ; Tianjin, PEOPLES R CHINA ; Web of Science
关键词laser-tissue interactions Monte Carlo bioheat transfer dynamic properties OPTICAL-PROPERTIES TISSUE Biophysics Optics Physics, Applied Imaging Science & Photographic Technology Spectroscopy
中文摘要To describe the complex nonlinear process of laser tissue interactions during laser-induced interstitial thermotherapy (LITT), a two-dimensional mathematical model considering the dynamic changes in the physical tissue properties was developed. A modified Monte Carlo method was developed to simulate photon transport in tissue with a non-uniform optical property field. the finite volume method was used to numerically solve the Penties bioheat equation to calculate the temperature distribution and the Arrhenius equation was used to predict the thermal damage extent. A temperature control heating method was also incorporated into present model to simulate the LITT clinical treatment to increase thermal damage volume and avoid evaporation and carbonization. The numerical results showed that the dynamic changes in the optical properties, the thermal properties and the blood perfusion rate significantly affected the damage volume accumulation in tissue and should be included in numerical simulations of the LITT treatment.
会议录出版者SPIE-INT SOC OPTICAL ENGINEERING ; BELLINGHAM ; 1000 20TH ST, PO BOX 10, BELLINGHAM, WA 98227-0010 USA
语种英语 ; 英语
内容类型会议论文
源URL[http://hdl.handle.net/123456789/19601]  
专题清华大学
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Jiang, S. C.,Zhang, X. X.. Mathematical modeling of dynamic laser coagulation during laser-induced interstitial thermotherapy - art. no. 604709[C]. 见:Fourth International Conference on Photonics and Imaging in Biology and Medicine, Pts 1 and 2, 4th International Conference on Photonics and Imaging in Biology and Medicine, Tianjin, PEOPLES R CHINA, Web of Science.
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