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	Preconcentration of Furosemide by cloud point extraction
	Huang Yan ; Qin Wei ; Huo Xiaoping ; Dai Youyuan
	2010-05-07 ; 2010-05-07
关键词	Theoretical or Mathematical Experimental/ chemical engineering sodium compounds surfactants/ cloud point extraction polyoxyethylene lauryl ether Furosemide sodium sulfate surfactant solution ambient temperature salt concentration preconcentration factor diuretic/ E3626 Chemical industry E1525 Industrial processes E1710 Engineering materials
中文摘要	A cloud point extraction process (CPE) utilizing polyoxyethylene 10 lauryl ether (C/sub 12/E/sub 10/) was developed to extract the diuretic, Furosemide. The effect of the concentrations of sodium sulfate, C/sub 12/E/sub 10/, and Furosemide as well as the temperature on the CPE behavior were investigated. The CPE process was improved by reducing the cloud point of the surfactant solution at ambient temperature with sodium sulfate. The preconcentration factor increases with the salt concentration, but the Furosemide extraction efficiency is independent of the salt concentration. Increasing the initial C/sub 12/E/sub 10/ concentration improves the extraction efficiency, but reduces the preconcentration factor by quickly increasing the coacervate phase mass. The tests also show that the preconcentration factor could be enhanced by increasing the temperature to 30 degrees C degrees 50 degrees C. A high preconcentration factor of 165.3 and coacervate to aqueous phase volume ratio of 0.0037 are achieved using 2 g middot L/sup -1/ C/sub 12/E/sub 10/ and 125 g middot L/sup -1/ sodium sulfate au 40 degrees C.
语种	中文 ; 中文
出版者	Tsinghua Univ. Press ; China
内容类型	期刊论文
源URL	[http://hdl.handle.net/123456789/17330]
专题	清华大学
推荐引用方式 GB/T 7714	Huang Yan,Qin Wei,Huo Xiaoping,et al. Preconcentration of Furosemide by cloud point extraction[J],2010, 2010.
APA	Huang Yan,Qin Wei,Huo Xiaoping,&Dai Youyuan.(2010).Preconcentration of Furosemide by cloud point extraction..
MLA	Huang Yan,et al."Preconcentration of Furosemide by cloud point extraction".(2010).

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