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Synthesis and Cytotoxicity of Nitrogen Mustard/Tripolypyrrole Conjugate
Ye, Yong ; Liu, Cun-Jiang ; Liu, Yan-Hong ; Cao, Li-Feng ; Zhao, Yu-Fen
2010-05-06 ; 2010-05-06
关键词POLYMERASE-II TRANSCRIPTION DNA MINOR-GROOVE STRUCTURAL BASIS BASE-PAIRS RECOGNITION LIGANDS CELLS Chemistry, Organic
中文摘要A series of nitrogen mustard derivatives were synthesized by chloroform reaction and coupling reaction using DCC/HOBT as promoting additives. The structure of compound was confirmed by H-1 NMR, P-31 NMR, MS and IR. The data show that the nitrogen mustard with tripolypyrrole as the linker inhibits all the four tested cells and has the highest activity.
语种英语 ; 英语
出版者HETERO CORPORATION ; PROVO ; PO BOX 170, PROVO, UT 84603-0170 USA
内容类型期刊论文
源URL[http://hdl.handle.net/123456789/13249]  
专题清华大学
推荐引用方式
GB/T 7714
Ye, Yong,Liu, Cun-Jiang,Liu, Yan-Hong,et al. Synthesis and Cytotoxicity of Nitrogen Mustard/Tripolypyrrole Conjugate[J],2010, 2010.
APA Ye, Yong,Liu, Cun-Jiang,Liu, Yan-Hong,Cao, Li-Feng,&Zhao, Yu-Fen.(2010).Synthesis and Cytotoxicity of Nitrogen Mustard/Tripolypyrrole Conjugate..
MLA Ye, Yong,et al."Synthesis and Cytotoxicity of Nitrogen Mustard/Tripolypyrrole Conjugate".(2010).
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