| Copper-catalyzed coupling of tertiary aliphatic amines with terminal alkynes to propargylamines via C-H activation | |
| Niu, Mingyu ; Yin, Zhengming ; Fu, Hua ; Jiang, Yuyang ; Zhao, Yufen | |
| 2010-05-06 ; 2010-05-06 | |
| 关键词 | CATION POOL METHOD NITROGEN ATOM BOND ACTIVATION ORGANIC-SYNTHESIS 3-COMPONENT SYNTHESIS OXIDATIVE ACTIVATION METHYLENE-COMPOUNDS N-BROMOSUCCINIMIDE SODIUM-CYANIDE BETA-LACTAMS Chemistry, Organic |
| 中文摘要 | We have developed a convenient and efficient method for coupling of tertiary aliphatic amines with terminal alkynes to propargylamines via C-H activation. The protocol uses CuBr as the catalyst, NBS as the free radical initiator, CH3CN as the solvent, and the alkynylation was selectively performed on the methyl of tertiary aliphatic amines at 80 degrees C. This is an economical and practical method for the synthesis of propargylamines. |
| 语种 | 英语 ; 英语 |
| 出版者 | AMER CHEMICAL SOC ; WASHINGTON ; 1155 16TH ST, NW, WASHINGTON, DC 20036 USA |
| 内容类型 | 期刊论文 |
| 源URL | [http://hdl.handle.net/123456789/12388]  |
| 专题 | 清华大学 |
| 推荐引用方式 GB/T 7714 | Niu, Mingyu,Yin, Zhengming,Fu, Hua,et al. Copper-catalyzed coupling of tertiary aliphatic amines with terminal alkynes to propargylamines via C-H activation[J],2010, 2010. |
| APA | Niu, Mingyu,Yin, Zhengming,Fu, Hua,Jiang, Yuyang,&Zhao, Yufen.(2010).Copper-catalyzed coupling of tertiary aliphatic amines with terminal alkynes to propargylamines via C-H activation.. |
| MLA | Niu, Mingyu,et al."Copper-catalyzed coupling of tertiary aliphatic amines with terminal alkynes to propargylamines via C-H activation".(2010). |
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