Triterpenoids of Chrysosplenium carnosum | |
Lu, Meng-ya1; Liao, Zhi-xin1; Ji, Lan-ju2; Sun, Hong-fa2 | |
刊名 | fitoterapia |
2013-03-01 | |
卷号 | 85页码:119-124 |
关键词 | Chrysosplenium carnosum Hook. f. et Thoms. Triterpenoid Anti-tumor activity |
英文摘要 | a phytochemical study of the ethanolic extract of chrysosplenium carnosum hook. f. et thoms. led to the isolation of two new oleanane-type triterpenoids, 6 beta-hydroxy-3-oxoolean-12-en-27-oic acid (1) and 3 beta, 21 alpha-dihydroxyolean-12-en-27-oic acid (2), along with fourteen known compounds (3-16), all of which were isolated from this plant for the first time. the structures of these compounds were established on the basis of spectroscopic methods. compounds 1-4 were evaluated for their in vitro anti-tumor activities on b16f10, sp2/0 and hep-g2 cells lines. compounds 1,3 and 4 exhibited strong inhibitory activity against b16f10 and sp2/0 cells' growth, compared with moderate cytotoxic activity against hep-g2 cells. however, compound 2 showed to be inactive against these tumor cells. (c) 2013 elsevier b.v. all rights reserved. |
WOS标题词 | science & technology ; life sciences & biomedicine |
类目[WOS] | chemistry, medicinal ; pharmacology & pharmacy |
研究领域[WOS] | pharmacology & pharmacy |
关键词[WOS] | aceriphyllum-rossii ; astilbe-chinensis ; flavonoids ; cytotoxicity ; grayanum ; cells |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000317172000018 |
内容类型 | 期刊论文 |
源URL | [http://ir.nwipb.ac.cn/handle/363003/6681] |
专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
作者单位 | 1.Southeast Univ, Sch Chem & Chem Engn, Dept Pharmaceut Engn, Nanjing 211189, Jiangsu, Peoples R China 2.Chinese Acad Sci, Northweast Inst Plateau Biol, Xining 810008, Peoples R China |
推荐引用方式 GB/T 7714 | Lu, Meng-ya,Liao, Zhi-xin,Ji, Lan-ju,et al. Triterpenoids of Chrysosplenium carnosum[J]. fitoterapia,2013,85:119-124. |
APA | Lu, Meng-ya,Liao, Zhi-xin,Ji, Lan-ju,&Sun, Hong-fa.(2013).Triterpenoids of Chrysosplenium carnosum.fitoterapia,85,119-124. |
MLA | Lu, Meng-ya,et al."Triterpenoids of Chrysosplenium carnosum".fitoterapia 85(2013):119-124. |
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