Graphene oxide: A potential bodyguard protecting proteins from photosensitive damage

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	Graphene oxide: A potential bodyguard protecting proteins from photosensitive damage
	Zhao, JF; Zhang, BW; Yu, CH; Liu, YC; Wang, WF; Li, JY
刊名	CARBON
	2016
卷号	109 页码:487-494
ISSN号	0008-6223
通讯作者	Wang, WF ; Li, JY (reprint author), Chinese Acad Sci, Shanghai Inst Appl Phys, 2019 Jialuo Rd, Shanghai 201800, Peoples R China.
英文摘要	Oxidative damage of proteins or DNA strands induced by UV irradiation certainly brings inflammation, gene mutation, immunosuppression, even causes carcinogenesis to creatures. Here, we show that graphene oxide nanosheets (GONs) can significantly reduce the photosensitizer-mediated oxidative damage of proteins, caused by UV irradiation. GONs act as absorbers, physically shielding the proteins from UV light, but they participate in the photochemical reactions between photo-activated species and proteins as well. They quench transient species of photosensitizers by energy transfer and electron transfer, reduce highly toxic singlet oxygen yield and repair damaged protein residues. Our results may help revise and broaden previous findings concerning photochemical behavior and photo-biological effects of GONs. (C) 2016 Elsevier Ltd. All rights reserved.
收录类别	SCI
语种	英语
WOS记录号	WOS:000385900100056
内容类型	期刊论文
源URL	[http://ir.sinap.ac.cn/handle/331007/26523]
专题	上海应用物理研究所_中科院上海应用物理研究所2011-2017年
推荐引用方式 GB/T 7714	Zhao, JF,Zhang, BW,Yu, CH,et al. Graphene oxide: A potential bodyguard protecting proteins from photosensitive damage[J]. CARBON,2016,109:487-494.
APA	Zhao, JF,Zhang, BW,Yu, CH,Liu, YC,Wang, WF,&Li, JY.(2016).Graphene oxide: A potential bodyguard protecting proteins from photosensitive damage.CARBON,109,487-494.
MLA	Zhao, JF,et al."Graphene oxide: A potential bodyguard protecting proteins from photosensitive damage".CARBON 109(2016):487-494.