Highly Efficient Direct Allylation of Oxindoles with Simple Allylic Alcohols Enabled by Palladium/Bronsted Acid Catalysis

CORC > 兰州化学物理研究所 > 中国科学院兰州化学物理研究所 > OSSO国家重点实验室

	Highly Efficient Direct Allylation of Oxindoles with Simple Allylic Alcohols Enabled by Palladium/Bronsted Acid Catalysis
	Yang HM(杨化萌)1; Zhou H(周慧)2,3; Yin, Hongyu 1; Xia CG(夏春谷)1 ; Jiang GX(蒋高喜)1,2
刊名	SYNLETT
	2014
卷号	25 期号:15 页码:2149-2154
关键词	oxindole allylic alkylation Bronsted acids allylic alcohol palladium
ISSN号	0936-5214
通讯作者	蒋高喜
英文摘要	A highly efficient and practical direct allylic alkylation of oxindoles with simple allylic alcohols cocatalyzed by Pd(OAc)₂/Ph₃P and PhCO₂H under mild conditions has been developed, which streamlines the installation of an all-carbon quaternary allylic center at the oxindole 3-position. Enantioselective allylic alkylation has also been realized with the product in almost quantitative yield and 17% enantiomeric excess. Mechanistically, ESI analysis indicates that a palladium(0) species and π-allyl-Pd(PPh₃)₂ cation were involved.
学科主题	物理化学与绿色催化
收录类别	SCI
资助信息	Hundred Talent Program of Chinese Academy of Sciences (CAS);the National Natural Science Foundation of China (21202175)
语种	英语
WOS记录号	WOS:000342570700012
内容类型	期刊论文
源URL	[http://210.77.64.217/handle/362003/21332]
专题	兰州化学物理研究所_OSSO国家重点实验室
作者单位	1.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Suzhou Inst Nanotech & Nanobion, Fax Suzhou 215123, Peoples R China 3.Chinese Acad Sci, Grad Univ, Beijing, Peoples R China
推荐引用方式 GB/T 7714	Yang HM,Zhou H,Yin, Hongyu,et al. Highly Efficient Direct Allylation of Oxindoles with Simple Allylic Alcohols Enabled by Palladium/Bronsted Acid Catalysis[J]. SYNLETT,2014,25(15):2149-2154.
APA	Yang HM,Zhou H,Yin, Hongyu,Xia CG,&Jiang GX.(2014).Highly Efficient Direct Allylation of Oxindoles with Simple Allylic Alcohols Enabled by Palladium/Bronsted Acid Catalysis.SYNLETT,25(15),2149-2154.
MLA	Yang HM,et al."Highly Efficient Direct Allylation of Oxindoles with Simple Allylic Alcohols Enabled by Palladium/Bronsted Acid Catalysis".SYNLETT 25.15(2014):2149-2154.