Magnesium whitlockite hollow microspheres: a comparison of microwave-hydrothermal and conventional hydrothermal syntheses using fructose 1,6-bisphosphate, and application in protein adsorption | |
Qi, Chao1; Chen, Feng1; Wu, Jin1; Zhu, Ying-Jie1; Hao, Chang-Ning2; Duan, Jun-Li3 | |
刊名 | RSC ADVANCES
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2016 | |
卷号 | 6期号:40页码:33393-33402 |
英文摘要 | Magnesium whitlockite (WH: Ca18Mg2(HPO4)(2)(PO4)(12)) is an abundant and biologically important biomineral in living bone, but the synthesis of single-phase WH hollow microspheres (WHHMs) still remains a challenge. In this paper, we report the environmentally friendly rapid microwave-assisted hydrothermal synthesis of WHHMs using fructose 1,6-bisphosphate trisodium salt as a biocompatible organic phosphorus source. In addition, the conventional hydrothermal method is also adopted for the synthesis of WHHMs, and the two synthetic methods are compared and discussed. The effects of the synthesis methods and experimental conditions on the crystal phase, morphology, stability and cytotoxicity of the products are investigated. The results indicate that the as-prepared WHHMs have a high biocompatibility. Moreover, the as-synthesized WHHMs are explored for potential application in protein adsorption by using hemoglobin (Hb) as a model protein, and they exhibit a relatively high protein adsorption capacity, thus, they are promising for applications in various biomedical fields such as protein adsorption. |
WOS标题词 | Science & Technology ; Physical Sciences |
类目[WOS] | Chemistry, Multidisciplinary |
研究领域[WOS] | Chemistry |
关键词[WOS] | ASSISTED RAPID SYNTHESIS ; 5'-TRIPHOSPHATE DISODIUM SALT ; BETA-TRICALCIUM PHOSPHATE ; RESPONSIVE DRUG-DELIVERY ; SONOCHEMICAL SYNTHESIS ; POROUS MICROSPHERES ; PHOSPHORUS SOURCE ; TRISODIUM SALT ; IN-VITRO ; CALCIUM |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000374045000021 |
内容类型 | 期刊论文 |
源URL | [http://ir.sic.ac.cn/handle/331005/23040] ![]() |
专题 | 上海硅酸盐研究所_生物材料与组织工程研究中心_期刊论文 |
作者单位 | 1.Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China 2.Shanghai Jiao Tong Univ, Sch Med, Ren Ji Hosp, Dept Vasc Surg, Shanghai 200127, Peoples R China 3.Shanghai Jiao Tong Univ, Sch Med, Xin Hua Hosp, Shanghai 200092, Peoples R China |
推荐引用方式 GB/T 7714 | Qi, Chao,Chen, Feng,Wu, Jin,et al. Magnesium whitlockite hollow microspheres: a comparison of microwave-hydrothermal and conventional hydrothermal syntheses using fructose 1,6-bisphosphate, and application in protein adsorption[J]. RSC ADVANCES,2016,6(40):33393-33402. |
APA | Qi, Chao,Chen, Feng,Wu, Jin,Zhu, Ying-Jie,Hao, Chang-Ning,&Duan, Jun-Li.(2016).Magnesium whitlockite hollow microspheres: a comparison of microwave-hydrothermal and conventional hydrothermal syntheses using fructose 1,6-bisphosphate, and application in protein adsorption.RSC ADVANCES,6(40),33393-33402. |
MLA | Qi, Chao,et al."Magnesium whitlockite hollow microspheres: a comparison of microwave-hydrothermal and conventional hydrothermal syntheses using fructose 1,6-bisphosphate, and application in protein adsorption".RSC ADVANCES 6.40(2016):33393-33402. |
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