Simultaneous qualitative and quantitative analysis of fluoroalkyl sulfonates in riverine water by liquid chromatography coupled with Orbitrap high resolution mass spectrometry

CORC > 生态环境研究中心 > 中国科学院生态环境研究中心 > 环境化学与生态毒理学国家重点实验室

	Simultaneous qualitative and quantitative analysis of fluoroalkyl sulfonates in riverine water by liquid chromatography coupled with Orbitrap high resolution mass spectrometry
	Lin, Yongfeng; Liu, Runzeng; Hu, Fanbao; Liu, Ruirui; Ruan, Ting; Jiang, Guibin
刊名	JOURNAL OF CHROMATOGRAPHY A
	2016-02-26
卷号	1435 期号:0 页码:66-74
关键词	Perfluoroalkyl sulfonates Fluorotelomer sulfonates LC-MS/MS High resolution mass spectrometry Tribrid Orbitrap Riverine water
英文摘要	In this study, a robust method for quick screening, confirmation and quantification analysis of eight fluoroalkyl sulfonates in surface riverine samples was developed using ultra-high performance liquid chromatography-high resolution mass spectrometer (LC-Orbitrap Tribrid HRMS). Weak anion exchange solid phase extraction was optimized to maximum recover perfluoroalkyl sulfonates (PFSAs), fluorotelomer sulfonates and the emerging 6:2 chlorinated polyfluoroalkyl ether sulfonate at the same time. Both qualitative and quantitative purposes could be achieved by simultaneous acquiring full-scan mass spectrum (MS1) and data-dependent MS2 data. The LC-Orbitrap Tribrid HRMS method showed competent method detection limits for all analytes (7.1-62 pg/L) compared with the triple quadrupole mass spectrometry (LC-MS/MS) quantification method (12-54 pg/L), and satisfactory method validation results were also obtained in linearity (R-2 > 0.999), trueness (88-118%), precision (2-17%) and recovery (63-103%). A good correlation (R > 0.999) was found between the sets of quantified PFSA residue concentrations in thirteen estuary river samples by both the LC-Orbitrap Tribrid HRMS (0.2-440 ng/L) and LC-MS/MS (0.1-424 ng/L) methods, indicating that Orbitrap Tribrid HRMS could be used for reliable quantitative analysis purpose. Moreover, the LC-Orbitrap Tribrid HRMS method could also benefit from its high mass resolution characteristic to eliminate potential environment interferents (e.g., taurodeoxycholate) and to quantify all PFSA isomers based on full-scan MS1 chromatogram at a narrow MS window (5 part per million). (C) 2016 Elsevier B.V. All rights reserved.
收录类别	SCI
内容类型	期刊论文
源URL	[http://ir.rcees.ac.cn/handle/311016/35947]
专题	生态环境研究中心_环境化学与生态毒理学国家重点实验室
推荐引用方式 GB/T 7714	Lin, Yongfeng,Liu, Runzeng,Hu, Fanbao,et al. Simultaneous qualitative and quantitative analysis of fluoroalkyl sulfonates in riverine water by liquid chromatography coupled with Orbitrap high resolution mass spectrometry[J]. JOURNAL OF CHROMATOGRAPHY A,2016,1435(0):66-74.
APA	Lin, Yongfeng,Liu, Runzeng,Hu, Fanbao,Liu, Ruirui,Ruan, Ting,&Jiang, Guibin.(2016).Simultaneous qualitative and quantitative analysis of fluoroalkyl sulfonates in riverine water by liquid chromatography coupled with Orbitrap high resolution mass spectrometry.JOURNAL OF CHROMATOGRAPHY A,1435(0),66-74.
MLA	Lin, Yongfeng,et al."Simultaneous qualitative and quantitative analysis of fluoroalkyl sulfonates in riverine water by liquid chromatography coupled with Orbitrap high resolution mass spectrometry".JOURNAL OF CHROMATOGRAPHY A 1435.0(2016):66-74.