Environmental Occurrence and Toxicology of Fluorotelomer Alcohols

CORC > 生态环境研究中心 > 中国科学院生态环境研究中心 > 环境化学与生态毒理学国家重点实验室

	Environmental Occurrence and Toxicology of Fluorotelomer Alcohols
	Li Zhongmin; Guo Lianghong
刊名	PROGRESS IN CHEMISTRY
	2016-07
卷号	28 期号:7 页码:993-1005
关键词	fluorotelomer alcohol poly- and perfluoroalkyl substances environmental pollution biotransformation toxicological effects
英文摘要	Poly- and perfluoroalkyl substances (PFASs) are a family of anthropogenic chemicals widely used in the commercial and industrial applications due to their unique properties of stability, hydrophobicity and lipophobicity. Traditionally, PFASs are produced via two major manufacturing processes; electrochemical fluorination (ECF) and telomerization. Due to their persistence, toxicity and bioaccumulation, ECF-associated chemicals perfluorooctane sulfonic acid (PFOS), its salts and perfluorooctane sulfonyl fluoride (POSF) are placed into the Annex B of the Stockholm Convention (SC) on Persistent Organic Pollutants (POPs) in 2009. The ECF production has also been phased out gradually in the developed countries. However, the production of fluorotelomer alcohols (FTOHs) by telomerization has increased significantly. Recent studies have demonstrated that the biotransformation and abiotic transformation of FTOHs yielded perfluocarboxylic acids (PFCAs), which may be router for the ubiquitous distribution of PFCAs. Besides, some of the FTOHs intermediate metabolites have been demonstrated to be able to covalently bind with various biomolecules and thereby cause serious toxicity, while the final metabolites are showed to cause hepatotoxicity and renal toxicity. Recently, the environmental problems related to FTOHs have become the hotspots in environmental science, toxicology and epidemiology. This paper reviews the research progress on the production status, environmental occurrence, and the toxicities of FTOHs and the related metabolites. Finally, the currently existing problems and trends are discussed.
收录类别	SCI
内容类型	期刊论文
源URL	[http://ir.rcees.ac.cn/handle/311016/35849]
专题	生态环境研究中心_环境化学与生态毒理学国家重点实验室
推荐引用方式 GB/T 7714	Li Zhongmin,Guo Lianghong. Environmental Occurrence and Toxicology of Fluorotelomer Alcohols[J]. PROGRESS IN CHEMISTRY,2016,28(7):993-1005.
APA	Li Zhongmin,&Guo Lianghong.(2016).Environmental Occurrence and Toxicology of Fluorotelomer Alcohols.PROGRESS IN CHEMISTRY,28(7),993-1005.
MLA	Li Zhongmin,et al."Environmental Occurrence and Toxicology of Fluorotelomer Alcohols".PROGRESS IN CHEMISTRY 28.7(2016):993-1005.