Chemical Fingerprint Analysis and Quantitative Analysis of Rosa rugosa by UPLC-DAD

CORC > 新疆理化技术研究所 > 中国科学院新疆理化技术研究所 > 省部共建新疆特有药用资源利用重点实验室

	Chemical Fingerprint Analysis and Quantitative Analysis of Rosa rugosa by UPLC-DAD
	Mansur, S (Mansur, Sanawar); Abdulla, R (Abdulla, Rahima); Ayupbec, A (Ayupbec, Amatjan); Aisa, HA (Aisa, Haji Akbar)
刊名	MOLECULES
	2016
卷号	21 期号:2
关键词	Rosa rugosa UPLC-DAD quality control fingerprint
通讯作者	Aisa, HA
英文摘要	A method based on ultra performance liquid chromatography with a diode array detector (UPLC-DAD) was developed for quantitative analysis of five active compounds and chemical fingerprint analysis of Rosa rugosa. Ten batches of R. rugosa collected from different plantations in the Xinjiang region of China were used to establish the fingerprint. The feasibility and advantages of the used UPLC fingerprint were verified for its similarity evaluation by systematically comparing chromatograms with professional analytical software recommended by State Food and Drug Administration (SFDA) of China. In quantitative analysis, the five compounds showed good regression (R-2 = 0.9995) within the test ranges, and the recovery of the method was in the range of 94.2%-103.8%. The similarities of liquid chromatography fingerprints of 10 batches of R. rugosa were more than 0.981. The developed UPLC fingerprint method is simple, reliable, and validated for the quality control and identification of R. rugosa. Additionally, simultaneous quantification of five major bioactive ingredients in the R. rugosa samples was conducted to interpret the consistency of the quality test. The results indicated that the UPLC fingerprint, as a characteristic distinguishing method combining similarity evaluation and quantification analysis, can be successfully used to assess the quality and to identify the authenticity of R. rugosa.
收录类别	SCI
WOS记录号	WOS:000392140100148
内容类型	期刊论文
源URL	[http://ir.xjipc.cas.cn/handle/365002/4715]
专题	新疆理化技术研究所_省部共建新疆特有药用资源利用重点实验室新疆理化技术研究所_资源化学研究室
作者单位	1.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Key Lab Xinjiang Indigenous Med Plants Resource U, Urumqi 830011, Peoples R China 2.Chinese Acad Sci, Xinjiang Tech Inst Phys & Chem, Key Lab Plant Resources & Chem Arid Reg, Urumqi 830011, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Mansur, S ,Abdulla, R ,Ayupbec, A ,et al. Chemical Fingerprint Analysis and Quantitative Analysis of Rosa rugosa by UPLC-DAD[J]. MOLECULES,2016,21(2).
APA	Mansur, S ,Abdulla, R ,Ayupbec, A ,&Aisa, HA .(2016).Chemical Fingerprint Analysis and Quantitative Analysis of Rosa rugosa by UPLC-DAD.MOLECULES,21(2).
MLA	Mansur, S ,et al."Chemical Fingerprint Analysis and Quantitative Analysis of Rosa rugosa by UPLC-DAD".MOLECULES 21.2(2016).