A quantum dot-based microRNA nanosensor for point mutation assays

	A quantum dot-based microRNA nanosensor for point mutation assays
	Zeng, Ya-ping; Zhu, Guichi; Yang, Xiao-yun; Cao, Jun; Jing, Zhi-liang; Zhang, Chun-yang
刊名	CHEMICAL COMMUNICATIONS
	2014
英文摘要	We have developed a quantum dot-based microRNA nanosensor for point mutation assays using primer generation-mediated rolling circle amplification. The proposed method exhibits high sensitivity with a detection limit of as low as 50.9 aM and a large dynamic range of 7 orders of magnitude from 0.1 fM to 1 nM. Importantly, this method can be further applied to analyze the point mutation of mir-196a2 in the lung tissues of non small-cell lung cancer patients.
收录类别	SCI
原文出处	http://pubs.rsc.org/en/Content/ArticleLanding/2014/CC/c4cc02034k#!divAbstract
语种	英语
内容类型	期刊论文
源URL	[http://ir.siat.ac.cn:8080/handle/172644/6127]
专题	深圳先进技术研究院_医药所
作者单位	CHEMICAL COMMUNICATIONS
推荐引用方式 GB/T 7714	Zeng, Ya-ping,Zhu, Guichi,Yang, Xiao-yun,et al. A quantum dot-based microRNA nanosensor for point mutation assays[J]. CHEMICAL COMMUNICATIONS,2014.
APA	Zeng, Ya-ping,Zhu, Guichi,Yang, Xiao-yun,Cao, Jun,Jing, Zhi-liang,&Zhang, Chun-yang.(2014).A quantum dot-based microRNA nanosensor for point mutation assays.CHEMICAL COMMUNICATIONS.
MLA	Zeng, Ya-ping,et al."A quantum dot-based microRNA nanosensor for point mutation assays".CHEMICAL COMMUNICATIONS (2014).