Promoter methylation of tumor suppressor genes in esophageal sguamous cell carcinoma

	Promoter methylation of tumor suppressor genes in esophageal sguamous cell carcinoma
	Ji-Sheng Li; Jian-Ming Ying; Xiu-Wen Wang; Zhao-Hui Wang; Qian Tao; Li-Li Li
刊名	Chines journal of cancer
	2013
英文摘要	Esophageal squamous cell carcinoma (ESCC) is a prevalent and fatal cancer in China and other Asian countries. Epigenetic silencing of key tumor suppressor genes (TSGs) is critical to ESCC initiation and progression. Recently, many novel TSGs silenced by promoter methylation have been identified in ESCC, and these genes further serve as potential tumor markers for high-risk group stratification, early detection, and prognosis prediction. This review summarizes recent discoveries on aberrant promoter methylation of TSGs in ESCC, providing better understanding of the role of disrupted epigenetic regulation in tumorigenesis and insight into diagnostic and prognostic biomarkers for this malignancy.
收录类别	其他
原文出处	http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3845589/
语种	英语
内容类型	期刊论文
源URL	[http://ir.siat.ac.cn:8080/handle/172644/5169]
专题	深圳先进技术研究院_医药所
作者单位	Chines journal of cancer
推荐引用方式 GB/T 7714	Ji-Sheng Li,Jian-Ming Ying,Xiu-Wen Wang,et al. Promoter methylation of tumor suppressor genes in esophageal sguamous cell carcinoma[J]. Chines journal of cancer,2013.
APA	Ji-Sheng Li,Jian-Ming Ying,Xiu-Wen Wang,Zhao-Hui Wang,Qian Tao,&Li-Li Li.(2013).Promoter methylation of tumor suppressor genes in esophageal sguamous cell carcinoma.Chines journal of cancer.
MLA	Ji-Sheng Li,et al."Promoter methylation of tumor suppressor genes in esophageal sguamous cell carcinoma".Chines journal of cancer (2013).