Hybrid gold–gadolinium nanoclusters for tumor-targeted NIRF/CT/MRI triple-modal imaging in vivo

	Hybrid gold–gadolinium nanoclusters for tumor-targeted NIRF/CT/MRI triple-modal imaging in vivo
	Hu, De-Hong; Sheng, Zong-Hai; Zhang, Peng-Fei; Yang, Da-Zhi; Liu, Shu-Hui; Gong, Ping; Gao, Du-Yang; Fang, Sheng-Tao; Ma, Yi-Fan; Cai, Lin-Tao
刊名	NANOSCALE
	2013
英文摘要	Multimodal imaging is highly desirable for accurate diagnosis because it can provide complementary information from each imaging modality. In this study, we prepared hybrid gold-gadolinium nanoclusters (NCs), which are ultrasmall, stable, biocompatible, and suitable for triple-modal NIRF/CT/MRI imaging. Upon intravenously injected, the hybrid NCs are effectively accumulated in tumor tissues and quickly clear by renal excretion, indicating their capacity of tumortargeting and low body residues. Notably, the ultrasmall hybrid NCs would penetrate into the solid tumor for capturing its heterostructure and do not induce potential toxicity in vivo. Hence, the well-defined hybrid gold-gadolinium NCs provide a versatile nanoprobe for cancer targeted imaging and diagnosis in vivo.
收录类别	SCI
原文出处	http://pubs.rsc.org/en/content/articlehtml/2012/nr/c2nr33543c
语种	英语
内容类型	期刊论文
源URL	[http://ir.siat.ac.cn:8080/handle/172644/5149]
专题	深圳先进技术研究院_医药所
作者单位	NANOSCALE
推荐引用方式 GB/T 7714	Hu, De-Hong,Sheng, Zong-Hai,Zhang, Peng-Fei,et al. Hybrid gold–gadolinium nanoclusters for tumor-targeted NIRF/CT/MRI triple-modal imaging in vivo[J]. NANOSCALE,2013.
APA	Hu, De-Hong.,Sheng, Zong-Hai.,Zhang, Peng-Fei.,Yang, Da-Zhi.,Liu, Shu-Hui.,...&Cai, Lin-Tao.(2013).Hybrid gold–gadolinium nanoclusters for tumor-targeted NIRF/CT/MRI triple-modal imaging in vivo.NANOSCALE.
MLA	Hu, De-Hong,et al."Hybrid gold–gadolinium nanoclusters for tumor-targeted NIRF/CT/MRI triple-modal imaging in vivo".NANOSCALE (2013).