A Universal Quantum Dots-Aptamer Probe for Efficient Cancer Detection and Targeted Imaging
Shuhong Lian; Pengfei Zhang; Ping Gong; Dehong Hu; Bihua Shi; Changchun Zeng; Lintao Cai
刊名JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
2012
英文摘要Targeted quantum dots have shown as an analytical and imaging tool for cancer detection and molecular imaging. Aptamers have recently been demonstrated as ideal candidates for molecular targeting applications. In the present work, quantum dots (QDs) were encapsulated with functional poly(ethylene glycol)-phospholipids to improve their solubility in water solution. The as-prepared QDs were then conjugated with the AS1411 aptamer recognizing the nucleolin overexpressed on cancer cell surface. The recognition of QD-Aptamer nanocomplex to breast cancer cells was demonstrated using confocal microscopy, and the viability of QD
收录类别SCI
原文出处https://www.researchgate.net/publication/235667567_A_Universal_Quantum_Dots-Aptamer_Probe_for_Efficient_Cancer_Detection_and_Targeted_Imaging
语种英语
内容类型期刊论文
源URL[http://ir.siat.ac.cn:8080/handle/172644/4292]  
专题深圳先进技术研究院_医药所
作者单位JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
推荐引用方式
GB/T 7714
Shuhong Lian,Pengfei Zhang,Ping Gong,et al. A Universal Quantum Dots-Aptamer Probe for Efficient Cancer Detection and Targeted Imaging[J]. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY,2012.
APA Shuhong Lian.,Pengfei Zhang.,Ping Gong.,Dehong Hu.,Bihua Shi.,...&Lintao Cai.(2012).A Universal Quantum Dots-Aptamer Probe for Efficient Cancer Detection and Targeted Imaging.JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY.
MLA Shuhong Lian,et al."A Universal Quantum Dots-Aptamer Probe for Efficient Cancer Detection and Targeted Imaging".JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY (2012).
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