CD3D and PRKCQ work together to discriminate between B-cell and T-cell acute lymphoblastic leukemia.

	CD3D and PRKCQ work together to discriminate between B-cell and T-cell acute lymphoblastic leukemia.
	Ma, Dongli; Zhong, Shan; Liu, Xiaorong; Mai, Huirong; Mai, Guoqin; Xu, Cheng; Zhou, Fengfeng
刊名	COMPUTERS IN BIOLOGY AND MEDICINE
	2016
英文摘要	Different therapeutic methods have been developed for the B-cell and T-cell subtypes of acute lymphoblastic leukemia (ALL). The identification of molecular biomarkers that can accurately discriminate between B-cell and T-cell ALLs will facilitate the quick determination of therapeutic plans, as well as reveal the intrinsic mechanisms underlining the two different ALL subtypes. This study computationally screened the high-throughput transcriptome dataset for multiple candidate biomarkers and verified their discrimination abilities in an independent sample set using quantitative real-time polymerase chain reaction (PCR) technology. Both technologies suggest that the two genes CD3D and PKRCQ together provided a good model for classification of B-cell and T-cell ALLs, whereas the individual genes did not show consistent discrimination between the two ALL subtypes. Supplementary material is available at http://healthinformaticslab.org/supp/.
收录类别	SCI
原文出处	http://www.sciencedirect.com/science/article/pii/S0010482516301809
语种	英语
内容类型	期刊论文
源URL	[http://ir.siat.ac.cn:8080/handle/172644/10404]
专题	深圳先进技术研究院_医工所
作者单位	COMPUTERS IN BIOLOGY AND MEDICINE
推荐引用方式 GB/T 7714	Ma, Dongli,Zhong, Shan,Liu, Xiaorong,et al. CD3D and PRKCQ work together to discriminate between B-cell and T-cell acute lymphoblastic leukemia.[J]. COMPUTERS IN BIOLOGY AND MEDICINE,2016.
APA	Ma, Dongli.,Zhong, Shan.,Liu, Xiaorong.,Mai, Huirong.,Mai, Guoqin.,...&Zhou, Fengfeng.(2016).CD3D and PRKCQ work together to discriminate between B-cell and T-cell acute lymphoblastic leukemia..COMPUTERS IN BIOLOGY AND MEDICINE.
MLA	Ma, Dongli,et al."CD3D and PRKCQ work together to discriminate between B-cell and T-cell acute lymphoblastic leukemia.".COMPUTERS IN BIOLOGY AND MEDICINE (2016).