Combinational effect of mutational bias and translational selection for translation efficiency in tomato (Solanum lycopersicum) cv. Micro-Tom

	Combinational effect of mutational bias and translational selection for translation efficiency in tomato (Solanum lycopersicum) cv. Micro-Tom
	Gaurav Sablok; XianMing Wu; Jimmy Kuo; Kinshuk Chandra Nayak; Vesselin Baev; Claudio Varotto; Fengfeng Zhou
刊名	GENOMICS
	2013
英文摘要	We conducted a comprehensive analysis of codon usage bias (CUB) based on the available non-redundant full-length cDNA (nrFLcDNA) and expressed sequence tags (ESTs) data of cultivar Micro-Tom and evaluated the associations of observed CUB and measurements of transcriptional and translational effectiveness. The analysis presented in our study suggests a correlation, which is negative but highly correlated between Axis 1 and GC3s (r = − 0.827, P < 0.01), indicating that mutational bias has a significant and dominant repressive role to the choices of GC3. We also observed a strong positive correlation between codon adaptation index (CAI) and translational adaptation index (tAIg) (0.407, P < 0.01), which demonstrates the facilitation of efficient translation by the optimal codon usage patterns of the highly expressed genes. We believe that the complete set of optimal codon usage patterns detected in this study will serve as a model to enhance the transgenesis in the studied cultivar of Solanum lycopersicum.
收录类别	SCI
原文出处	http://www.sciencedirect.com/science/article/pii/S0888754313000372
语种	英语
内容类型	期刊论文
源URL	[http://ir.siat.ac.cn:8080/handle/172644/4834]
专题	深圳先进技术研究院_医工所
作者单位	GENOMICS
推荐引用方式 GB/T 7714	Gaurav Sablok,XianMing Wu,Jimmy Kuo,et al. Combinational effect of mutational bias and translational selection for translation efficiency in tomato (Solanum lycopersicum) cv. Micro-Tom[J]. GENOMICS,2013.
APA	Gaurav Sablok.,XianMing Wu.,Jimmy Kuo.,Kinshuk Chandra Nayak.,Vesselin Baev.,...&Fengfeng Zhou.(2013).Combinational effect of mutational bias and translational selection for translation efficiency in tomato (Solanum lycopersicum) cv. Micro-Tom.GENOMICS.
MLA	Gaurav Sablok,et al."Combinational effect of mutational bias and translational selection for translation efficiency in tomato (Solanum lycopersicum) cv. Micro-Tom".GENOMICS (2013).