Clinical Effects of Xinmailong Therapy in Patients with Chronic Heart Failure

	Clinical Effects of Xinmailong Therapy in Patients with Chronic Heart Failure
	Qilin Ma; Youxi Luo; Pi Guo; Gan Gao; Meixue Yang; Gaurav Sablok; Yanchun Zhang; Fengfeng Zhou
刊名	INTERNATIONAL JOURNAL OF MEDICAL SCIENCES
	2013
英文摘要	In the last 100 years, intensive studies have been done on the identification of the systematic approaches to find the cure for the chronic heart failure, however the mystery remains unresolved due to its complicated pathogenesis and ineffective early diagnosis. The present investigation was aimed to evaluate the potential effects of the traditional chinese medicine, Xinmailong, on the chronic heart failure (CHF) patients as compared to the standard western medical treatment available so far. In our study, we selected two groups of voluntary CHF patients at the Xiangya Hospital, which were allowed to administrate Xinmailong or standard treatments, respectively. Another group of voluntary healthy individuals were recruited as the control group. The treatment effectiveness was measured by five symptomatic factors, i.e. angiotensin II (Ang_II), high sensitivity C-reactive protein (hs_CRP), Left Ventricular End Systolic Volume Index (LVESVI), left ventricular ejection fraction (LVEF) and pro-B-type natriuretic peptide (NT_proBNP), between the control group and the CHF patients at different stages of drug administration and in different treatment groups. The timeline for the full dose administration was set to 15 days and five measurements as indicated above were taken on every 0, 7th and 15th day of the drug administration respectively. In the conducted study, similar symptomatic measurements were observed on day 0 in both treatment groups, and slight improvements were observed on 7th day. It was observed that after a full course of drug administration for 15 days, both of the treatment groups achieved statistically significant improvements in all the five measures, but Xinmailong was found to be more (almost double) statistically significant as compared with the available drug treatments for chronic heart failure.
收录类别	SCI
原文出处	http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619101/
语种	英语
内容类型	期刊论文
源URL	[http://ir.siat.ac.cn:8080/handle/172644/4833]
专题	深圳先进技术研究院_医工所
作者单位	INTERNATIONAL JOURNAL OF MEDICAL SCIENCES
推荐引用方式 GB/T 7714	Qilin Ma,Youxi Luo,Pi Guo,et al. Clinical Effects of Xinmailong Therapy in Patients with Chronic Heart Failure[J]. INTERNATIONAL JOURNAL OF MEDICAL SCIENCES,2013.
APA	Qilin Ma.,Youxi Luo.,Pi Guo.,Gan Gao.,Meixue Yang.,...&Fengfeng Zhou.(2013).Clinical Effects of Xinmailong Therapy in Patients with Chronic Heart Failure.INTERNATIONAL JOURNAL OF MEDICAL SCIENCES.
MLA	Qilin Ma,et al."Clinical Effects of Xinmailong Therapy in Patients with Chronic Heart Failure".INTERNATIONAL JOURNAL OF MEDICAL SCIENCES (2013).