Microbubble displacement under ultrasonic chirp excitation

	Microbubble displacement under ultrasonic chirp excitation
	Yi Hu; YunGe; DongZhang; HaiRongZheng; XiuFenGong
刊名	ACTA PHYSICA SINICA
	2009
卷号	58 期号:7 页码:4746-4751
英文摘要	Ultrasound radiation force has been shown promising in facilitating ultrasonic molecular imaging and target drug delivery. A chirp excitation technique is developed to improve the translational displacement of microbubbles in this study. Based on a modified RP equation and a particle trajectory equation, we investigate the dependence of the translation of microbubble clouds on the chirp parameters (center frequency and frequency shift) and bubble radius distribution. Results demonstrate that the chirp excitation performs better than the traditional sinusoidal excitation in displacing widely distributed microbubbles and bubble clouds with radius far from resonant size. For example, for Gaussian size-distributed microbubble clouds with mean radius 3.5 mu m and variance of I, a 1 MHz center frequency chirp with frequency range 0.75 MHz induces about 12% more microbubbles displaced over a distance of 30 mu m during 200 mu s insonification, compared with a I MHz sinusoidal excitation with equal acoustic pressure.
收录类别	SCI
原文出处	http://apps.webofknowledge.com/full_record.do?product=WOS&search_mode=GeneralSearch&qid=27&SID=T2qqaSmxThAAdG9j2sp&page=1&doc=1
语种	英语
内容类型	期刊论文
源URL	[http://ir.siat.ac.cn:8080/handle/172644/2530]
专题	深圳先进技术研究院_医工所
作者单位	ACTA PHYSICA SINICA
推荐引用方式 GB/T 7714	Yi Hu,YunGe,DongZhang,et al. Microbubble displacement under ultrasonic chirp excitation[J]. ACTA PHYSICA SINICA,2009,58(7):4746-4751.
APA	Yi Hu,YunGe,DongZhang,HaiRongZheng,&XiuFenGong.(2009).Microbubble displacement under ultrasonic chirp excitation.ACTA PHYSICA SINICA,58(7),4746-4751.
MLA	Yi Hu,et al."Microbubble displacement under ultrasonic chirp excitation".ACTA PHYSICA SINICA 58.7(2009):4746-4751.