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	Mapping the transmural scar and activation for patients with ventricular arrhythmia
	Linwei Wang; Fady Dawoud; Ken CL Wong; Heye Zhang; Huafeng Liu; John Sapp; Milan Horacek; Pengcheng Shi
	2011
会议名称	Computing in Cardiology 2011, CinC 2011
会议地点	Hangzhou, China
英文摘要	Myocardial scar is the most common substrate for malignant arrhythmia and cardiac arrest. Radiofrequency ablation, as one of the emerging mainstream therapies, currently relies on electrophysiologic (EP) map acquired on endocardial and occasionally epicardial surfaces. As myocardial scar is often complexwith shapes varying with the depth of the myocardium, endocardial and epicardial maps may differ substantially, and may fail to identify mid-wall fibrosis that exist in similar to 30% of patients with nonischemic cardiomyopathy. Alternative image-based delineation of anatomical scar is noninvasive and transmural, but it does not reflect the possibly EP functional anomaly. In this paper, we present a validation study of a previously developed method that combines body-surface electrocardiographic data and image-derived anatomic data to compute EP and scar details along the depth of the myocardium. Experiments were performed on 4 patients referred for ablation associated with myocardial infarction, with gold standards of substrate voltage maps and activation maps acquired by CARTO electroanatomic mapping system. This study exhibits the ability of the presented method in accurately quantifying the scar substrate and capturing abnormal EP patterns, not only on the heart surfaces but along the transmural dimension.
收录类别	EI
语种	英语
内容类型	会议论文
源URL	[http://ir.siat.ac.cn:8080/handle/172644/3347]
专题	深圳先进技术研究院_集成所
作者单位	2011
推荐引用方式 GB/T 7714	Linwei Wang,Fady Dawoud,Ken CL Wong,et al. Mapping the transmural scar and activation for patients with ventricular arrhythmia[C]. 见:Computing in Cardiology 2011, CinC 2011. Hangzhou, China.

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