Application of Multimodal MR Imaging on Studying Alzheimer's Disease: A Survey.

	Application of Multimodal MR Imaging on Studying Alzheimer's Disease: A Survey.
	Wang Defeng; Hui Steve C. N.; Shi Lin; Huang Wen-hua; Wang Tianfu; Mok Vincent C. T.; Chu Winnie C. W.; Ahuja, Anil T.
刊名	CURRENT ALZHEIMER RESEARCH
	2013
英文摘要	The aim of this review is to summarize the current magnetic resonance imaging (MRI) variants applied on the studies of Alzheimer's disease (AD). Experimental findings, advantages and disadvantages, and the prospect of every individual technique will be presented. MRI can be used to investigate the change of the brain in terms of volume, function, white matter track orientation and even mechanical properties and metabolic concentration.Results from volumetric and morphological analysis indicated that the hippocampus reduced by approximately 18%-24% or 3%-4% annually. Functional MRI (fMRI) detected the blood oxygen level dependent (BOLD) signaland suggested thatmedial temporal lobe (MTL) such as hippocampus and entorhinal cortex reduced at the early stage of AD, and frontal, temporal, and parietal cortices at the later stage. In diffusion tensor imaging (DTI), the white matter fiber track integrity is measured but the results are inconsistent. Besides,magnetic resonance spectroscopy (MRS), chemical shift imaging (CSI), arterial spin labeling (ASL), magnetic resonance elastography (MRE) and susceptibility weighted imaging (SWI) will also be included in this review.
收录类别	SCI
原文出处	http://chinesesites.library.ingentaconnect.com/content/ben/car/2013/00000010/00000008/art00010
语种	英语
内容类型	期刊论文
源URL	[http://ir.siat.ac.cn:8080/handle/172644/4426]
专题	深圳先进技术研究院_集成所
作者单位	CURRENT ALZHEIMER RESEARCH
推荐引用方式 GB/T 7714	Wang Defeng,Hui Steve C. N.,Shi Lin,et al. Application of Multimodal MR Imaging on Studying Alzheimer's Disease: A Survey.[J]. CURRENT ALZHEIMER RESEARCH,2013.
APA	Wang Defeng.,Hui Steve C. N..,Shi Lin.,Huang Wen-hua.,Wang Tianfu.,...&Ahuja, Anil T..(2013).Application of Multimodal MR Imaging on Studying Alzheimer's Disease: A Survey..CURRENT ALZHEIMER RESEARCH.
MLA	Wang Defeng,et al."Application of Multimodal MR Imaging on Studying Alzheimer's Disease: A Survey.".CURRENT ALZHEIMER RESEARCH (2013).