Antibacterial ability and hemocompatibility of graphene functionalized germanium | |
Geng, Hao1,3; Dai, Jiayun2,3; Li, Jinhua1,3; Di, Zengfeng2; Liu, Xuanyong1 | |
刊名 | SCIENTIFIC REPORTS |
2016-11-23 | |
卷号 | 6 |
英文摘要 | Germanium (Ge), as an elemental semiconductor material, has been an attractive candidate for manufacturing semiconductor microelectronic device. In the present investigation, to improve the biocompatibility of Ge-based device, graphene film is directly deposited on the Ge surface with different coverage area by controlling the growth time. Compared to bare Ge, the presence of graphene film entitles Ge with satisfactory antibacterial ability against Staphylococcus aureus (S. aureus), and acceptable antibacterial ability against Escherichia coli (E. coli). Meanwhile, antibacterial efficiency closely correlates with coverage area of graphene film, and larger graphene coverage always leads to better antibacterial performance. The underlying mechanism is thought to be the integrative action of phospholipids disturbance and electron extraction at the interface between graphene and biomembrane. Meanwhile, the electron extraction action would further lead to the activation of platelet. This study might provide some new insights into the relationship between antibacterial ability and hemocompatibility based on graphene functionalized biomedical device. |
WOS标题词 | Science & Technology |
类目[WOS] | Multidisciplinary Sciences |
研究领域[WOS] | Science & Technology - Other Topics |
关键词[WOS] | TITANIUM-OXIDE FILMS ; BLOOD COMPATIBILITY ; CELLS ; BIOSENSORS ; NANOSHEETS ; MEMBRANES ; BACTERIA ; SILICON ; SURFACE ; APATITE |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000388347400001 |
内容类型 | 期刊论文 |
源URL | [http://ir.sic.ac.cn/handle/331005/21977] |
专题 | 上海硅酸盐研究所_生物材料与组织工程研究中心_期刊论文 |
作者单位 | 1.Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Microsyst & Informat Technol, State Key Lab Funct Mat Informat, Shanghai 200050, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Geng, Hao,Dai, Jiayun,Li, Jinhua,et al. Antibacterial ability and hemocompatibility of graphene functionalized germanium[J]. SCIENTIFIC REPORTS,2016,6. |
APA | Geng, Hao,Dai, Jiayun,Li, Jinhua,Di, Zengfeng,&Liu, Xuanyong.(2016).Antibacterial ability and hemocompatibility of graphene functionalized germanium.SCIENTIFIC REPORTS,6. |
MLA | Geng, Hao,et al."Antibacterial ability and hemocompatibility of graphene functionalized germanium".SCIENTIFIC REPORTS 6(2016). |
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