Tree shrew database (TreeshrewDB): a genomic knowledge base for the Chinese tree shrew

CORC > 昆明动物研究所 > 昆明动物研究所 > 动物模型与人类重大疾病机理重点实验室 > 重大疾病机理的遗传学

	Tree shrew database (TreeshrewDB): a genomic knowledge base for the Chinese tree shrew
	Fan Y 1,2; Yu DD 1; Yao YG[*]1,2,3
刊名	SCIENTIFIC REPORTS
	2014
卷号	4 期号:X 页码:e7145
通讯作者	ygyaozh@gmail.com
合作状况	其它
英文摘要	The tree shrew (Tupaia belangeri) is a small mammal with a close relationship to primates and it has been proposed as an alternative experimental animal to primates in biomedical research. The recent release of a high-quality Chinese tree shrew genome enables more researchers to use this species as the model animal in their studies. With the aim to making the access to an extensively annotated genome database straightforward and easy, we have created the Tree shrew Database (TreeshrewDB). This is a web-based platform that integrates the currently available data from the tree shrew genome, including an updated gene set, with a systematic functional annotation and a mRNA expression pattern. In addition, to assist with automatic gene sequence analysis, we have integrated the common programs Blast, Muscle, GBrowse, GeneWise and codeml, into TreeshrewDB. We have also developed a pipeline for the analysis of positive selection. The user-friendly interface of TreeshrewDB, which is available at http://www.treeshrewdb.org, will undoubtedly help in many areas of biological research into the tree shrew.
收录类别	SCI
资助信息	This study was supported by the National 863 Project of China(2012AA021801)andgrants from Chinese Academy of Sciences (KSCX2-EW-R-11 and KSCX2-EW-J23) and Yunnan Province (2013FB071).
语种	英语
WOS记录号	WOS:000346178900002
公开日期	2015-01-09
内容类型	期刊论文
源URL	[http://159.226.149.42:8088/handle/152453/8214]
专题	昆明动物研究所_重大疾病机理的遗传学昆明动物研究所_动物模型与人类重大疾病机理重点实验室昆明动物研究所_中国科学院昆明灵长类研究中心
作者单位	1.Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology,Kunming, Yunnan 650223, China 2.Kunming College of Life Science, University ofChinese Academy of Sciences, Kunming, Yunnan 650223, China 3.Kunming Primate Research Center, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China
推荐引用方式 GB/T 7714	Fan Y,Yu DD,Yao YG[*]. Tree shrew database (TreeshrewDB): a genomic knowledge base for the Chinese tree shrew[J]. SCIENTIFIC REPORTS,2014,4(X):e7145.
APA	Fan Y,Yu DD,&Yao YG[*].(2014).Tree shrew database (TreeshrewDB): a genomic knowledge base for the Chinese tree shrew.SCIENTIFIC REPORTS,4(X),e7145.
MLA	Fan Y,et al."Tree shrew database (TreeshrewDB): a genomic knowledge base for the Chinese tree shrew".SCIENTIFIC REPORTS 4.X(2014):e7145.