Sequence Variation of Melanocortin 1 Receptor (MC1R) Gene and Association with Plumage Color in Domestic Geese

CORC > 昆明动物研究所 > 昆明动物研究所 > 动物模型与人类重大疾病机理重点实验室 > 重大疾病机理的遗传学

	Sequence Variation of Melanocortin 1 Receptor (MC1R) Gene and Association with Plumage Color in Domestic Geese
	Huang J 1; Zhou B 1; He DQ 2; Chen SY 1; Zhu Q 1; Yao YG 3; Liu YP[*]1
刊名	JOURNAL OF POULTRY SCIENCE
	2014
卷号	51 期号:3 页码:270-274
关键词	SNPs Zhedong white goose Landes goose MCIR plumage color
通讯作者	liuyp578@yahoo.com
合作状况	其它
英文摘要	In contrast to other domestic and wild animals, the genetic variation of MC1R gene and association with plumage color has not been investigated in domestic goose. In the present study, we sequenced 714 bp fragment of the MC1R for 176 individuals from two goose breeds with three plumage color pattern (Landes goose, gray plumage, n=58; Landes goose, spotted plumage, near black, n=36; Zhedong White Goose, white plumage, n=82). A total of five single nucleotide polymorphisms (SNPs) were detected, including c.210C>T, c.321C>T, c.411C>T, c.525C>T, and c.756G>A, which subsequently determined seven haplotypes (H1-H7). Among them, H2 and H4 were the predominant haplotypes. Association analysis revealed that haplotypes H2 and H5 were significantly associated with white plumage of Zhedong white goose, whereas H3 was significantly associated with gray plumage in Landes goose (p<0.01). Diplotypes H2H2 and H3H4 were associated with white plumage in Zhedong white goose and gray plumage in Landes goose (p <0.01), respectively. The results suggested that the genetic variation of MC1R is also significantly associated with the plumage color in domestic goose.
资助信息	This study was supported by the National Natural Science Foundation of China (31172181), the Program for New Century Excellent Talent in University (NCET-10-0889), Sichuan Province (2011JTD0032; 11TD007), Yunnan Prov- ince (2009CI119) and the Ministry of Agriculture of China (2009ZX08009-159B)
语种	英语
WOS记录号	WOS:000339471600005
公开日期	2014-10-15
内容类型	期刊论文
源URL	[http://159.226.149.42:8088/handle/152453/8033]
专题	昆明动物研究所_重大疾病机理的遗传学昆明动物研究所_动物模型与人类重大疾病机理重点实验室
作者单位	1.College of Animal Science and Technology, Sichuan Agricultural University, Ya’an, Sichuan 625014 China 2.Institute of Animal Husbandry and Veterinary Medicine, Shanghai Academy of Agricultural Sciences, Shanghai 201106, China 3.Key Laboratory of Animal Models and Human Disease Mechanisms, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan 650223 China
推荐引用方式 GB/T 7714	Huang J,Zhou B,He DQ,et al. Sequence Variation of Melanocortin 1 Receptor (MC1R) Gene and Association with Plumage Color in Domestic Geese[J]. JOURNAL OF POULTRY SCIENCE,2014,51(3):270-274.
APA	Huang J.,Zhou B.,He DQ.,Chen SY.,Zhu Q.,...&Liu YP[*].(2014).Sequence Variation of Melanocortin 1 Receptor (MC1R) Gene and Association with Plumage Color in Domestic Geese.JOURNAL OF POULTRY SCIENCE,51(3),270-274.
MLA	Huang J,et al."Sequence Variation of Melanocortin 1 Receptor (MC1R) Gene and Association with Plumage Color in Domestic Geese".JOURNAL OF POULTRY SCIENCE 51.3(2014):270-274.