An update to MitoTool: Using a new scoring system for faster mtDNA haplogroup determination

CORC > 昆明动物研究所 > 昆明动物研究所 > 动物模型与人类重大疾病机理重点实验室 > 重大疾病机理的遗传学

	An update to MitoTool: Using a new scoring system for faster mtDNA haplogroup determination
	Fan L 1,2; Yao YG[*]1
刊名	MITOCHONDRION
	2013
卷号	13 期号:4 页码:360-363
关键词	mtDNA Haplogroup Determination Scoring system
通讯作者	mitotool@gmail.com ; ygyaozh@gmail.com
合作状况	其它
英文摘要	The determination of human mitochondrial DNA (mtDNA) haplogroups is not only crucial in anthropological and forensic studies, but is also helpful in the medical field to prevent establishment of wrong disease associations. In recent years, high-throughput technologies and the huge amounts of data they create, as well as the regular updates to the mtDNA phylogenetic tree, mean that there is a need for an automated approach which can make a speedier determination of haplogroups than can be made by using the traditional manual method. Here, we update the MitoTool (www.mitotool.org) by incorporating a novel scoring system for the determination of mtDNA into haplogroups, which has advantages on speed, accuracy and ease of implementation. In order to make the access to MitoTool easier, we also provide a stand-alone version of the program that will run on a local computer and this version is freely available at the MitoTool website. (C) 2013 Elsevier B.V. and Mitochondria Research Society.
收录类别	SCI
资助信息	This work was supported by the National Science Foundation of China (30925021), the Top Talents Program of Yunnan Province (2009CI119) and the Chinese Academy of Sciences.
语种	英语
WOS记录号	WOS:000320294600014
公开日期	2013-09-24
内容类型	期刊论文
源URL	[http://159.226.149.42:8088/handle/152453/7673]
专题	昆明动物研究所_重大疾病机理的遗传学昆明动物研究所_动物模型与人类重大疾病机理重点实验室
作者单位	1.Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan 650223, China. 2.School of Life Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong Special Administrative Region, China
推荐引用方式 GB/T 7714	Fan L,Yao YG[*]. An update to MitoTool: Using a new scoring system for faster mtDNA haplogroup determination[J]. MITOCHONDRION,2013,13(4):360-363.
APA	Fan L,&Yao YG[*].(2013).An update to MitoTool: Using a new scoring system for faster mtDNA haplogroup determination.MITOCHONDRION,13(4),360-363.
MLA	Fan L,et al."An update to MitoTool: Using a new scoring system for faster mtDNA haplogroup determination".MITOCHONDRION 13.4(2013):360-363.