Offline Memory Reprocessing: Involvement of the Brain's Default Network in Spontaneous Thought Processes

CORC > 昆明动物研究所 > 昆明动物研究所 > 动物模型与人类重大疾病机理重点实验室 > 学习记忆的分子神经机制

	Offline Memory Reprocessing: Involvement of the Brain's Default Network in Spontaneous Thought Processes
	Wang K 1; Yu CS 2; Xu L 3; Jiang TZ[*]1; Xu LJ 1; Qin W 2; Li KC 2
刊名	PLOS ONE
	2009
卷号	4 期号:3 页码:e4867
通讯作者	jiangtz@nlpr.ia.ac.cn
合作状况	其它
英文摘要	Background: Spontaneous thought processes (STPs), also called daydreaming or mind-wandering, occur ubiquitously in daily life. However, the functional significance of STPs remains largely unknown. Methodology/Principal Finding: Using functional magnetic resonance imaging (fMRI), we first identified an STPs-network whose activity was positively correlated with the subjects' tendency of having STPs during a task-free state. The STPs-network was then found to be strongly associated with the default network, which has previously been established as being active during the task-free state. Interestingly, we found that offline reprocessing of previously memorized information further increased the activity of the STPs-network regions, although during a state with less STPs. In addition, we found that the STPs-network kept a dynamic balance between functional integration and functional separation among its component regions to execute offline memory reprocessing in STPs. Conclusion/Significance: These findings strengthen a view that offline memory reprocessing and STPs share the brain's default network, and thus implicate that offline memory reprocessing may be a predetermined function of STPs. This supports the perspective that memory can be consolidated and modified during STPs, and thus gives rise to a dynamic behavior dependent on both previous external and internal experiences.
收录类别	SCI
资助信息	This work was supported by the Natural Science Foundation of China, Grant Nos. 30425004, and 60121302, the National Key Basic Research and Development Program (973), Grant No. 2004CB318107, Beijing Scientific and Technological New Star Program Grant No. 2005B21, and CAS graduate science and social practice special funding innovative research projects.
语种	英语
内容类型	期刊论文
源URL	[http://159.226.149.26:8080/handle/152453/10481]
专题	昆明动物研究所_学习记忆的分子神经机制
作者单位	1.National Laboratory of Pattern Recognition, Institute of Automation, Chinese Academy of Sciences, Beijing, People’s Republic of China 2.Department of Radiology, Xuanwu Hospital of Capital Medical University, Beijing, People’s Republic of China 3.Laboratory of Learning and Memory, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, People’s Republic of China
推荐引用方式 GB/T 7714	Wang K,Yu CS,Xu L,et al. Offline Memory Reprocessing: Involvement of the Brain's Default Network in Spontaneous Thought Processes[J]. PLOS ONE,2009,4(3):e4867.
APA	Wang K.,Yu CS.,Xu L.,Jiang TZ[*].,Xu LJ.,...&Li KC.(2009).Offline Memory Reprocessing: Involvement of the Brain's Default Network in Spontaneous Thought Processes.PLOS ONE,4(3),e4867.
MLA	Wang K,et al."Offline Memory Reprocessing: Involvement of the Brain's Default Network in Spontaneous Thought Processes".PLOS ONE 4.3(2009):e4867.