Honey bee microRNAs respond to infection by the microsporidian parasite Nosema ceranae

	Honey bee microRNAs respond to infection by the microsporidian parasite Nosema ceranae
	Huang Q[]1,2; Chen YP 2; Wang RW[]1; Schwarz RS 2; Evans JD[*]2
刊名	SCIENTIFIC REPORTS
	2015
卷号	5 期号:X 页码:e17494
通讯作者	qiang-huang@live.com ; wangrw@mail.kiz.ac.cn ; Jay.Evans@ARS.USDA.GOV
合作状况	其它
英文摘要	In order to study the effects of Nosema ceranae infection on honey bee microRNA (miRNA) expression, we deep-sequenced honey bee miRNAs daily across a full 6-day parasite reproduction cycle. Seventeen miRNAs were differentially expressed in honey bees infected by N. ceranae that potentially target over 400 genes predicted to primarily involve ion binding, signaling, the nucleus, transmembrane transport, and DNA binding. Based on Enzyme Code analysis, nine biological pathways were identified by screening target genes against the Kyoto Encyclopedia of Genes and Genomes (KEGG) database, seven of which involved metabolism. Our results suggest that differentially expressed miRNAs regulate metabolism related genes of host honey bees in response to N. ceranae infection.
收录类别	SCI
资助信息	The work is supported by USDA-NIFA grant 2014-67013-21784.
语种	英语
内容类型	期刊论文
源URL	[http://159.226.149.26:8080/handle/152453/9496]
专题	昆明动物研究所_实验与理论生态学昆明动物研究所_遗传资源与进化国家重点实验室
作者单位	1.State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China 2.USDA-ARS Bee Research Laboratory, BARC-East Building 306, Beltsville, Maryland, 20705, USA
推荐引用方式 GB/T 7714	Huang Q[],Chen YP,Wang RW[],et al. Honey bee microRNAs respond to infection by the microsporidian parasite Nosema ceranae[J]. SCIENTIFIC REPORTS,2015,5(X):e17494.
APA	Huang Q[],Chen YP,Wang RW[],Schwarz RS,&Evans JD[*].(2015).Honey bee microRNAs respond to infection by the microsporidian parasite Nosema ceranae.SCIENTIFIC REPORTS,5(X),e17494.
MLA	Huang Q[*],et al."Honey bee microRNAs respond to infection by the microsporidian parasite Nosema ceranae".SCIENTIFIC REPORTS 5.X(2015):e17494.