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Genomic Comparison of the Ants Camponotus floridanus and Harpegnathos saltator
Bonasio R1; Zhang GJ2,3; Ye CY4; Mutti NS5; Fang XD3; Qin N3; Donahue G4; Yang PC3; Li QY3; Li C3
刊名SCIENCE
2010
卷号329期号:5995页码:1068-1071
通讯作者bergers@mail.med.upenn.edu ; danny.reinberg@nyumc.org ; wangj@genomics.cn ; juergen.liebig@asu.edu
合作状况其它
英文摘要The organized societies of ants include short-lived worker castes displaying specialized behavior and morphology and long-lived queens dedicated to reproduction. We sequenced and compared the genomes of two socially divergent ant species: Camponotus floridanus and Harpegnathos saltator. Both genomes contained high amounts of CpG, despite the presence of DNA methylation, which in non-Hymenoptera correlates with CpG depletion. Comparison of gene expression in different castes identified up-regulation of telomerase and sirtuin deacetylases in longer-lived H. saltator reproductives, caste-specific expression of microRNAs and SMYD histone methyltransferases, and differential regulation of genes implicated in neuronal function and chemical communication. Our findings provide clues on the molecular differences between castes in these two ants and establish a new experimental model to study epigenetics in aging and behavior.
收录类别SCI
语种英语
内容类型期刊论文
源URL[http://159.226.149.26:8080/handle/152453/10451]  
专题昆明动物研究所_基因起源组
昆明动物研究所_遗传资源与进化国家重点实验室
作者单位1.Department of Biochemistry, New York University School of Medicine, 522 First Avenue, New York, NY 10016, USA
2.Chinese Academy of Sciences–Max Planck Junior Research Group, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy ofSciences,Kunming,Yunnan650223,China
3.BeijingGenomics Institute–Shenzhen, Shenzhen 518083, China
4.Department of Cell and Developmental Biology, University of Pennsylvania SchoolofMedicine,Philadelphia,PA19104,USA.
5.SchoolofLife Sciences, Arizona State University, Tempe, AZ 85287, USA.
6.HowardHughesMedicalInstitute,NewYorkUniversityMedical School, New York, NY 10016, USA
7.Department of Biology, University of Copenhagen, Copenhagen DK-2200, Denmark
推荐引用方式
GB/T 7714
Bonasio R,Zhang GJ,Ye CY,et al. Genomic Comparison of the Ants Camponotus floridanus and Harpegnathos saltator[J]. SCIENCE,2010,329(5995):1068-1071.
APA Bonasio R.,Zhang GJ.,Ye CY.,Mutti NS.,Fang XD.,...&Liebig J[*].(2010).Genomic Comparison of the Ants Camponotus floridanus and Harpegnathos saltator.SCIENCE,329(5995),1068-1071.
MLA Bonasio R,et al."Genomic Comparison of the Ants Camponotus floridanus and Harpegnathos saltator".SCIENCE 329.5995(2010):1068-1071.
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